Synonyms of low-gradenext
1
: of inferior grade or quality
2
: being near that extreme of a specified range which is lowest, least intense, least serious, or least competent
a low-grade fever
a low-grade infection

Examples of low-grade in a Sentence

plumbing fixtures that were made out of low-grade materials
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
For someone already carrying that kind of low-grade worry, a surprise $4,000 surgery bill is the type of shock that crushes a stable-looking budget. Sydney Lake, Fortune, 22 June 2026 Constant notifications, background noise and perpetual availability keep the body's sympathetic nervous system in a chronic low-grade fight-or-flight state. Bryan Robinson, Forbes.com, 21 June 2026 One idea scientists are investigating to help is to target inflammation (some research has shown about one-fourth of people who have depression show signs of low-grade inflammation) by altering how the immune system’s signaling proteins behave. Helen Carefoot, Flow Space, 17 June 2026 Exercise lowers chronic low-grade inflammation, reduces oxidative stress, increases endothelial production, and increases nitric oxide production in our vessels. Teresa Maalouf, Verywell Health, 12 June 2026 See All Example Sentences for low-grade

Word History

First Known Use

1877, in the meaning defined at sense 1

Time Traveler
The first known use of low-grade was in 1877

Browse Nearby Words

Cite this Entry

“Low-grade.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/low-grade. Accessed 27 Jun. 2026.

Kids Definition

low-grade

adjective
ˈlō-ˈgrād
1
: of poor grade or quality
2
: being near that end of a range which is lowest, weakest, or least able
a low-grade fever

Medical Definition

low-grade

adjective
: being near that extreme of a specified range which is lowest, least intense, or least competent
a low-grade fever
a low-grade infection
compare high-grade
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