high-grade

adjective

ˈhī-ˈgrād 

1

: of superior grade or quality

high-grade bonds

2

a

: being near the upper or most favorable extreme of a specified range

b

: medically serious or life-threatening

a high-grade tumor

Examples of high-grade in a Sentence

Recent Examples on the Web

Despite epic battery life, these invisible hearing aids aren’t ideal for users who want high-grade hearing support. —Christopher Null, Wired News, 11 Aug. 2025

With free trade, rare cheeses, exotic fruit, spices and high-grade meats stop becoming luxury goods consumed only by the wealthiest Americans and become more attainable to the average consumer. —Juan Londoño, Baltimore Sun, 10 Aug. 2025

Still, the Yankees faced a rotation crunch ahead of right-hander Luis Gil’s return last weekend from a high-grade lat strain that cropped up during spring training. —Peter Sblendorio, New York Daily News, 9 Aug. 2025

Low-grade and high-grade dysplasia: Pre-cancerous changes that require monitoring or treatment, Rahman says. —Elizabeth Yuko, Flow Space, 4 Aug. 2025

Word History

First Known Use

1826, in the meaning defined at sense 1

Rhymes for high-grade

• afraid
• allayed
• arcade
• arrayed
• assayed
• barmaid
• betrayed
• blockade
• bridesmaid
• brigade
• brocade
• buffeted

Kids Definition

high-grade

adjective

ˈhī-ˈgrād

: of a better grade or quality

Medical Definition

high-grade

adjective

ˈhī-ˈgrād 

: being near the upper, most serious, or most life-threatening extreme of a specified range

high-grade gliomas

high-grade cervical dysplasia

compare low-grade