1
: of superior grade or quality
high-grade bonds
2
a
: being near the upper or most favorable extreme of a specified range
b
: medically serious or life-threatening
a high-grade tumor

Examples of high-grade in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
After surgery to remove the tumor, a biopsy revealed that Ni had stage III-C high-grade serous ovarian cancer, an advanced stage of ovarian cancer. Ciara McCarthy 9, Fort Worth Star-Telegram, 9 Sep. 2025 Jonny Fine, who oversees high-grade debt underwriting at Goldman Sachs, tells me. Liz Hoffman, semafor.com, 9 Sep. 2025 To be specific, I was diagnosed with high-grade DCIS with micro-invasion. Janelle Ash, FOXNews.com, 9 Sep. 2025 Overall, the Pixel 10 Pro feels well-constructed with high-grade materials that help justify its price tag. PC Magazine, 4 Sep. 2025 See All Example Sentences for high-grade

Word History

First Known Use

1826, in the meaning defined at sense 1

Time Traveler
The first known use of high-grade was in 1826

Cite this Entry

“High-grade.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/high-grade. Accessed 18 Sep. 2025.

Kids Definition

high-grade

adjective
ˈhī-ˈgrād
: of a better grade or quality

Medical Definition

high-grade

adjective
: being near the upper, most serious, or most life-threatening extreme of a specified range
high-grade gliomas
high-grade cervical dysplasia
compare low-grade

More from Merriam-Webster on high-grade

Last Updated: - Updated example sentences
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