1
: of inferior grade or quality
2
: being near that extreme of a specified range which is lowest, least intense, least serious, or least competent
a low-grade fever
a low-grade infection
Examples of low-grade in a Sentence
plumbing fixtures that were made out of low-grade materials
Recent Examples on the Web
The Spirit had limited play from star player Trinity Rodman, who sustained a low-grade MCL sprain during a game last month and returned to action during the team's semifinal last week, when she was subbed in at the 90th minute of the match.
—
Anna Lazarus Caplan, PEOPLE, 23 Nov. 2025
So instead of a clarion call urging them to change, executives are hearing a series of low-grade alarms, constantly sounding and impossible to ever fully escape.
—David Podolsky, Fortune, 19 Nov. 2025
It’s known to trigger ongoing low-grade inflammation — the type of immune activity that may negatively impact how the body processes sugar, and even raise heart disease risk.
—Tom Gavin, EverydayHealth.com, 18 Nov. 2025
In addition to hurting your skin directly thanks to their impact on collagen and elastin, AGEs also hurt your skin indirectly by triggering oxidative stress and chronic low-grade inflammation—biological conditions that put strain on your whole body.
—Caroline Tien, SELF, 11 Nov. 2025
See All Example Sentences for low-grade
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Anna Lazarus Caplan, PEOPLE, 23 Nov. 2025
So instead of a clarion call urging them to change, executives are hearing a series of low-grade alarms, constantly sounding and impossible to ever fully escape.
—David Podolsky, Fortune, 19 Nov. 2025
It’s known to trigger ongoing low-grade inflammation — the type of immune activity that may negatively impact how the body processes sugar, and even raise heart disease risk.
—Tom Gavin, EverydayHealth.com, 18 Nov. 2025
In addition to hurting your skin directly thanks to their impact on collagen and elastin, AGEs also hurt your skin indirectly by triggering oxidative stress and chronic low-grade inflammation—biological conditions that put strain on your whole body.
—Caroline Tien, SELF, 11 Nov. 2025
See All Example Sentences for low-grade
Cite this Entry
“Low-grade.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/low-grade. Accessed 26 Nov. 2025.
Copy CitationMedical Definition
low-grade
adjective
: being near that extreme of a specified range which is lowest, least intense, or least competent
a low-grade fever
a low-grade infection
compare high-grade
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