loco

verb

locoed; locoing; locos
Synonyms of loconext

transitive verb

1
: to poison with locoweed
2
: to make frenzied

Examples of loco in a Sentence

years of living alone had clearly locoed the old rancher

Word History

First Known Use

1884, in the meaning defined at sense 1

Time Traveler
The first known use of loco was in 1884

Browse Nearby Words

Cite this Entry

“Loco.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/loco. Accessed 11 Jun. 2026.

Kids Definition

loco

adjective
lo·​co
ˈlō-kō
slang
: mentally disordered

Medical Definition

loco

1 of 2 noun
lo·​co ˈlō-(ˌ)kō How to pronounce loco (audio)
plural locos or locoes
: any of several plants (genera Astragalus and Oxytropis) of western North America that contain a toxin that causes locoism in livestock when ingested in large quantities : locoweed

loco

2 of 2 transitive verb
: to poison with locoweed
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