2
: an abnormal change in structure of an organ or part due to injury or disease
especially
: one that is circumscribed (see circumscribe sense 1) and well-defined
Examples of lesion in a Sentence
Recent Examples on the Web
Just two weeks ago, Gary Woodland decided ot shared his struggles with post traumatic stress disorder, brought on after a September 2023 surgery, which involved a baseball-sized hole cut from the side of his head, to remove a brain lesion.
—
Andrew McCarty, MSNBC Newsweek, 31 Mar. 2026
The lesion that was removed from his brain is from the part that causes moments of unfounded fear.
—Gary Bedore, Kansas City Star, 31 Mar. 2026
Surgery in September 2023, which involved a baseball-sized hole cut from the side of his head, removed much of the lesion.
—ABC News, 29 Mar. 2026
Its entry point on a tree is a crack, lesion, or other injury in the tree’s trunk or thick branches.
—Encyclopedia Britannica, 27 Mar. 2026
See All Example Sentences for lesion
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Andrew McCarty, MSNBC Newsweek, 31 Mar. 2026
The lesion that was removed from his brain is from the part that causes moments of unfounded fear.
—Gary Bedore, Kansas City Star, 31 Mar. 2026
Surgery in September 2023, which involved a baseball-sized hole cut from the side of his head, removed much of the lesion.
—ABC News, 29 Mar. 2026
Its entry point on a tree is a crack, lesion, or other injury in the tree’s trunk or thick branches.
—Encyclopedia Britannica, 27 Mar. 2026
See All Example Sentences for lesion
Cite this Entry
“Lesion.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lesion. Accessed 4 Apr. 2026.
Copy CitationKids Definition
lesion
noun
le·sion
ˈlē-zhən 
: a change in the structure of a bodily organ or part due to injury or disease
especially
: an injured or diseased spot or area clearly marked off from healthy tissue around it
Medical Definition
Legal Definition
lesion
noun
le·sion
ˈlē-zhən
in the civil law of Louisiana
: loss from failure to receive a threshold amount or value (as one-half market value) for immovable property conveyed or transferred by a commutative contract (as a sale or exchange)
called also lesion beyond moiety
compare unjust enrichmentEtymology
Anglo-French, damage, injury, from Latin laesio, from laedere to injure
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