cyclooxygenase

noun

cy·clo·ox·y·gen·ase | \ ˌsī-klō-ˈäk-si-jə-ˌnās

Definition of cyclooxygenase

: an enzyme that catalyzes the conversion of arachidonic acid to prostaglandins and that has two isoforms of which one is involved in the creation of prostaglandins which mediate inflammation and pain

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The first known use of cyclooxygenase was in 1974

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cyclooxygenase

noun

cy·clo·ox·y·gen·ase | \ ˌsī-klō-ˈäk-si-jə-ˌnās

, -äk-ˈsij-ə-

, -ˌnāz\

Medical Definition of cyclooxygenase

: an enzyme that catalyzes the conversion of arachidonic acid to prostaglandins, that is inactivated by aspirin and other NSAIDs, and that has two isoforms of which one is involved in the cascade of events producing the pain and inflammation of arthritis and the other is not — see cox-1, cox-2