cyclooxygenase

noun
cy·​clo·​ox·​y·​gen·​ase | \ ˌsī-klō-ˈäk-si-jə-ˌnās How to pronounce cyclooxygenase (audio) \

Definition of cyclooxygenase

: an enzyme that catalyzes the conversion of arachidonic acid to prostaglandins and that has two isoforms of which one is involved in the creation of prostaglandins which mediate inflammation and pain

First Known Use of cyclooxygenase

1974, in the meaning defined above

History and Etymology for cyclooxygenase

cycl- + oxygenase, an enzyme, from oxygen + -ase

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The first known use of cyclooxygenase was in 1974

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Cite this Entry

“Cyclooxygenase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cyclooxygenase. Accessed 21 Jan. 2021.

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More Definitions for cyclooxygenase

cyclooxygenase

noun
cy·​clo·​ox·​y·​gen·​ase | \ ˌsī-klō-ˈäk-si-jə-ˌnās How to pronounce cyclooxygenase (audio) , -äk-ˈsij-ə- How to pronounce cyclooxygenase (audio) , -ˌnāz \

Medical Definition of cyclooxygenase

: an enzyme that catalyzes the conversion of arachidonic acid to prostaglandins, that is inactivated by aspirin and other NSAIDs, and that has two isoforms of which one is involved in the cascade of events producing the pain and inflammation of arthritis and the other is not — see cox-1, cox-2

More from Merriam-Webster on cyclooxygenase

Britannica.com: Encyclopedia article about cyclooxygenase

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