cyclooxygenase

noun

cy·​clo·​ox·​y·​gen·​ase ˌsī-klō-ˈäk-si-jə-ˌnās How to pronounce cyclooxygenase (audio)
: an enzyme that catalyzes the conversion of arachidonic acid to prostaglandins and that has two isoforms of which one is involved in the creation of prostaglandins which mediate inflammation and pain

Examples of cyclooxygenase in a Sentence

Recent Examples on the Web That’s because curcumin inhibits an enzyme called cyclooxygenase, or COX, which creates a chemical that coats the stomach to prevent acid from triggering ulcers. Kristen Fischer, Health, 24 Sep. 2023

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'cyclooxygenase.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

cycl- + oxygenase, an enzyme, from oxygen + -ase

First Known Use

1974, in the meaning defined above

Time Traveler
The first known use of cyclooxygenase was in 1974

Dictionary Entries Near cyclooxygenase

Cite this Entry

“Cyclooxygenase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cyclooxygenase. Accessed 22 Jul. 2024.

Medical Definition

cyclooxygenase

noun
cy·​clo·​ox·​y·​gen·​ase ˌsī-klō-ˈäk-si-jə-ˌnās How to pronounce cyclooxygenase (audio) -äk-ˈsij-ə- How to pronounce cyclooxygenase (audio)
-ˌnāz
: an enzyme that catalyzes the conversion of arachidonic acid to prostaglandins, that is inactivated by aspirin and other NSAIDs, and that has two isoforms of which one is involved in the cascade of events producing the pain and inflammation of arthritis and the other is not see cox-1, cox-2

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