bisphosphonate

noun bis·phos·pho·nate \ ˌbis-ˈfäs-fə-ˌnāt \

Definition of bisphosphonate

: any of a group of drugs that slow the breakdown of bone by osteoclasts

Recent Examples of bisphosphonate from the Web

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Origin and Etymology of bisphosphonate

bis + phosphonic acid (an acid obtained from phosphine) + 1-ate


Medical Dictionary

bisphosphonate

noun bis·phos·pho·nate \ ˌbis-ˈfäs-fə-ˌnāt \

medical Definition of bisphosphonate

: any of a group of drugs (such as alendronate or etidronate) that slow the breakdown of bone by osteoclasts
  • … among the pharmacological approaches for treating osteoporosis, use of bisphosphonates increases bone mineral density and reduces the risk of vertebral fractures.
  • —Charles MarwickThe Journal of the American Medical Association26 Apr. 2000
called also diphosphonate
Note: Bisphonates
are analogs of pyrophosphate and contain two phosphate groups attached to a central carbon atom that replaces the oxygen atom in pyrophosphate.

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