anti-idiotype

noun

an·ti-id·io·type | \ ˌan-tē-ˈi-dē-ə-ˌtīp

, ˌan-tī-\

Definition of anti-idiotype

: an antibody that binds to the antigen-combining site of another antibody either suppressing or enhancing the immune response

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The first known use of anti-idiotype was in 1973

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anti-idiotype

noun

an·ti-id·io·type | \ ˌan-tī-ˈid-ē-ə-ˌtīp\

Medical Definition of anti-idiotype

: an antibody that binds to the antigen combining site of another antibody either suppressing or enhancing the immune response Anti-idiotypes are secondary antibodies manufactured by the immune system in reaction to the presence of antibodies, the body's basic germ fighters.— Craig D. Rose, The San Diego Union-Tribune, 11 Mar. 1988

Other Words from anti-idiotype

anti-idiotype or anti-idiotypic \ -ˌid-ē-ə-ˈtip-ik

\ adjective

Recent studies … indicate, however, that other cancer cells expressing a different idiotype can emerge during anti-idiotype treatment. — Ronald C. Kennedy et al., Scientific American, July 1986 Anti-idiotypic antibodies that bind to the idiotype marker (antigen-binding site) on B cells, may also suppress autoantibody production. — Jacqueline Parkin and Bryony Cohen, The Lancet, 2 June 2001

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