anti-idiotype

noun an·ti-id·io·type \ ˌan-tē-ˈi-dē-ə-ˌtīp , ˌan-tī- \

Definition of anti-idiotype

: an antibody that binds to the antigen-combining site of another antibody either suppressing or enhancing the immune response

anti-idiotypic

play \-ˌi-dē-ə-ˈti-pik\ adjective

First Known Use of anti-idiotype

1973


Medical Dictionary

anti-idiotype

noun an·ti-id·io·type \ ˌan-tī-ˈid-ē-ə-ˌtīp \

medical Definition of anti-idiotype

: an antibody that binds to the antigen combining site of another antibody either suppressing or enhancing the immune response
  • Anti-idiotypes are secondary antibodies manufactured by the immune system in reaction to the presence of antibodies, the body's basic germ fighters.
  • —Craig D. RoseThe San Diego Union-Tribune11 Mar. 1988

anti-idiotype

or anti-idiotypic play \-ˌid-ē-ə-ˈtip-ik\ adjective
    • Recent studies … indicate, however, that other cancer cells expressing a different idiotype can emerge during anti-idiotype treatment.
    • —Ronald C. Kennedy et al.Scientific AmericanJuly 1986
    • Anti-idiotypic antibodies that bind to the idiotype marker (antigen-binding site) on B cells, may also suppress autoantibody production.
    • —Jacqueline Parkin and Bryony CohenThe Lancet2 June 2001

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