anti-idiotype

noun

an·​ti-id·​io·​type ˌan-tē-ˈi-dē-ə-ˌtīp How to pronounce anti-idiotype (audio) ˌan-tī- How to pronounce anti-idiotype (audio)
: an antibody that binds to the antigen-combining site of another antibody either suppressing or enhancing the immune response
anti-idiotypic adjective

Word History

First Known Use

1973, in the meaning defined above

Time Traveler
The first known use of anti-idiotype was in 1973

Dictionary Entries Near anti-idiotype

Cite this Entry

“Anti-idiotype.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/anti-idiotype. Accessed 26 Feb. 2024.

Medical Definition

anti-idiotype

noun
an·​ti-id·​io·​type
ˌan-tī-ˈid-ē-ə-ˌtīp
: an antibody that binds to the antigen combining site of another antibody either suppressing or enhancing the immune response
Anti-idiotypes are secondary antibodies manufactured by the immune system in reaction to the presence of antibodies, the body's basic germ fighters.Craig D. Rose, The San Diego Union-Tribune
anti-idiotype adjective
or anti-idiotypic
Recent studies … indicate, however, that other cancer cells expressing a different idiotype can emerge during anti-idiotype treatment. Ronald C. Kennedy et al., Scientific American
Anti-idiotypic antibodies that bind to the idiotype marker (antigen-binding site) on B cells, may also suppress autoantibody production. Jacqueline Parkin and Bryony Cohen, The Lancet
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