Definition of anti-idiotype
:an antibody that binds to the antigen-combining site of another antibody either suppressing or enhancing the immune response
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First Known Use of anti-idiotype
1973
Medical Dictionary
anti-idiotype
noun
an·ti-id·io·type
\
ˌan-tī-ˈid-ē-ə-ˌtīp
\
medical Definition of anti-idiotype
:an antibody that binds to the antigen combining site of another antibody either suppressing or enhancing the immune response
- Anti-idiotypes are secondary antibodies manufactured by the immune system in reaction to the presence of antibodies, the body's basic germ fighters.
- —Craig D. Rose, The San Diego Union-Tribune, 11 Mar. 1988
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anti-idiotype
or anti-idiotypic play \-ˌid-ē-ə-ˈtip-ik\ adjective-
- Recent studies … indicate, however, that other cancer cells expressing a different idiotype can emerge during anti-idiotype treatment.
- —Ronald C. Kennedy et al., Scientific American, July 1986
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- Anti-idiotypic antibodies that bind to the idiotype marker (antigen-binding site) on B cells, may also suppress autoantibody production.
- —Jacqueline Parkin and Bryony Cohen, The Lancet, 2 June 2001
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