antagonistic

adjective

an·​tag·​o·​nis·​tic (ˌ)an-ˌta-gə-ˈni-stik 

: showing dislike or opposition : marked by or resulting from antagonism

an antagonistic relationship

factions antagonistic to one another

antagonistically

(ˌ)an-ˌta-gə-ˈni-sti-k(ə-)lē 

adverb

Synonyms

• hostile
• negative

Examples of antagonistic in a Sentence

They found it impossible to deal with such antagonistic groups.

countries that have been antagonistic towards each other for centuries

Recent Examples on the Web

Sawa played Scott Wormer, the leader of a group of antagonistic brothers who ultimately falls for Roberta. —Victoria Edel, PEOPLE, 22 Oct. 2025

Her daughter’s doctor (Bronstein) is openly antagonistic and makes noises about a change in care, whatever that means. —Bill Goodykoontz, AZCentral.com, 18 Oct. 2025

Are officers masked, armed, and antagonistic? —Nancy Gibbs, Time, 17 Oct. 2025

Across almost 20 novels, the British author spun fantastical tales with unsentimental wit, infusing his work with darkly morbid humor, blithe child endangerment, rotten and antagonistic adults, and a willingness to occasionally laugh at the misfortune of others. —Wilson Chapman, IndieWire, 17 Oct. 2025

Word History

Etymology

see antagonize

First Known Use

circa 1637, in the meaning defined above

Rhymes for antagonistic

• anachronistic
• animalistic
• antiphlogistic
• behavioristic
• cannibalistic
• capitalistic
• characteristic
• collectivistic
• deterministic
• ethnolinguistic
• expressionistic
• idealistic

Kids Definition

antagonistic

adjective

an·​tag·​o·​nis·​tic (ˌ)an-ˌtag-ə-ˈnis-tik 

: showing antagonism

antagonistically

-ti-k(ə-)lē 

adverb

Medical Definition

antagonistic

adjective

an·​tag·​o·​nis·​tic (ˌ)an-ˌtag-ə-ˈnis-tik 

1

: characterized by or resulting from antagonism

antagonistic antibiotics

2

: relating to or being muscles that are antagonists

skeletal muscles arranged in antagonistic pairs

antagonistically

-ti-k(ə-)lē 

adverb