antagonistic

adjective

an·​tag·​o·​nis·​tic (ˌ)an-ˌta-gə-ˈni-stik How to pronounce antagonistic (audio)
Synonyms of antagonisticnext
: showing dislike or opposition : marked by or resulting from antagonism
an antagonistic relationship
factions antagonistic to one another
antagonistically adverb

Examples of antagonistic in a Sentence

They found it impossible to deal with such antagonistic groups. countries that have been antagonistic towards each other for centuries
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Ali then exacts his revenge, pumping several rounds into Alamo's chest as the antagonistic figure falls for good. Joey Nolfi, Entertainment Weekly, 1 June 2026 The French and American film industries have always been symbiotic, if also a little antagonistic. Stephanie Zacharek, Time, 27 May 2026 Further, a separate gesture from De Paul that appeared antagonistic toward those supporters went uncaptured, as did Messi’s post-game maneuver to round up De Paul and Suarez, keeping them away explicitly from La Familia’s side of the stadium during post-game pleasantries. Ian Nicholas Quillen, Forbes.com, 22 May 2026 While Foote attempted to project positivity, his daily briefings were often unclear and antagonistic with the local media. Thomas Drance, New York Times, 19 May 2026 See All Example Sentences for antagonistic

Word History

Etymology

see antagonize

First Known Use

circa 1637, in the meaning defined above

Time Traveler
The first known use of antagonistic was circa 1637

Browse Nearby Words

Cite this Entry

“Antagonistic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antagonistic. Accessed 5 Jun. 2026.

Kids Definition

antagonistic

adjective
an·​tag·​o·​nis·​tic (ˌ)an-ˌtag-ə-ˈnis-tik How to pronounce antagonistic (audio)
: showing antagonism
antagonistically adverb

Medical Definition

antagonistic

adjective
an·​tag·​o·​nis·​tic (ˌ)an-ˌtag-ə-ˈnis-tik How to pronounce antagonistic (audio)
1
: characterized by or resulting from antagonism
antagonistic antibiotics
2
: relating to or being muscles that are antagonists
skeletal muscles arranged in antagonistic pairs
antagonistically adverb

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