antagonize

verb

an·​tag·​o·​nize an-ˈta-gə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing

transitive verb

1
: to incur or provoke the hostility of
His criticism antagonized his friends.
2
: to act in opposition to : counteract
The drug is antagonized by methylxanthines, such as caffeine and theophylline …Scientific American Medicine

Examples of antagonize in a Sentence

He didn't mean to antagonize you. Her comments antagonized many people.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Sliwa warned both were taking the wrong approach by antagonizing the president. Preston Fore, Fortune, 23 Oct. 2025 The president could always pursue a consensus solution to America’s immigration problem through Congress rather than antagonizing our communities with blunt force and unconstitutional military deployments. Newsweek Contributors, MSNBC Newsweek, 22 Oct. 2025 Jelinek, who portrayed supporting character Jay (a bully who, alongside actor Larry Bagby's Ice, antagonizes Katz's Max at the start of the film), remembers Katz courting him to get high before rehearsal for a key scene helmed by director Kenny Ortega. Joey Nolfi, Entertainment Weekly, 20 Oct. 2025 Bad Bunny’s Super Bowl performance comes at a time when the government has antagonized Latino communities, spread anti-Latino rhetoric, and treated immigrants with abject cruelty, callously celebrating images of forceful, often violent arrests and brutal detainments. Julyssa Lopez, Rolling Stone, 19 Oct. 2025 See All Example Sentences for antagonize

Word History

Etymology

Greek antagōnizesthai, from anti- + agōnizesthai to struggle, from agōn contest — more at agony

First Known Use

circa 1742, in the meaning defined at sense 2

Time Traveler
The first known use of antagonize was circa 1742

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Cite this Entry

“Antagonize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antagonize. Accessed 24 Oct. 2025.

Kids Definition

antagonize

verb
an·​tag·​o·​nize an-ˈtag-ə-ˌnīz How to pronounce antagonize (audio)
antagonized; antagonizing
: to stir up dislike or anger in

Medical Definition

antagonize

transitive verb
an·​tag·​o·​nize
variants also British antagonise
antagonized also British antagonised; antagonizing also British antagonising
: to act in antagonism to : counteract
these effects are antagonized by atropineErnest Bueding & Harry Most

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