molecule

noun

mol·​e·​cule ˈmä-li-ˌkyül How to pronounce molecule (audio)
1
: the smallest particle of a substance that retains all the properties (see property sense 1a) of the substance and is composed of one or more atoms (see atom sense 1a)
a molecule of water
a molecule of oxygen
2
: a tiny bit : particle
a molecule of political honestyTime

Examples of molecule in a Sentence

There is not a molecule of evidence to support these charges. not a molecule of sense in that girl
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The researchers then conducted a randomized clinical trial in humans, in which half of the participants received the NVG-291 drug, which contained a repair molecule to improve nervous system function. Angelica Stabile, FOXNews.com, 3 Oct. 2025 Within those grains, Khawaja and his team found not just frozen water, but the same organic molecules observed in the E-ring. Eric Lagatta, USA Today, 3 Oct. 2025 Massive volumes of ambient air move through a system containing a chemical agent that selectively binds to CO2 molecules. Tejasri Gururaj, Interesting Engineering, 3 Oct. 2025 But the helicase acts like a brake, causing the molecule to go through with a ratcheting motion, one base at a time, at a still-lively rate of about 400 bases per second. IEEE Spectrum, 2 Oct. 2025 See All Example Sentences for molecule

Word History

Etymology

French molécule, from New Latin molecula, diminutive of Latin moles mass

First Known Use

1701, in the meaning defined at sense 1

Time Traveler
The first known use of molecule was in 1701

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Cite this Entry

“Molecule.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/molecule. Accessed 5 Oct. 2025.

Kids Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
1
: the smallest particle of a substance having all the characteristics of the substance
a molecule of water
a molecule of oxygen
2
: a very small bit : particle

Medical Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
: the smallest particle of a substance that retains all the properties of the substance and is composed of one or more atoms

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