molecule

noun

mol·​e·​cule ˈmä-li-ˌkyül How to pronounce molecule (audio)
Synonyms of moleculenext
1
: the smallest particle of a substance that retains all the properties (see property sense 1a) of the substance and is composed of one or more atoms (see atom sense 1a)
a molecule of water
a molecule of oxygen
2
: a tiny bit : particle
There is a molecule of evidence to support these charges.

Examples of molecule in a Sentence

There is not a molecule of evidence to support these charges. not a molecule of sense in that girl
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
These nanosheets have a very high surface area and strong catalytic properties, helping ethanol molecules react more quickly on the sensor surface. Bojan Stojkovski, Interesting Engineering, 1 Feb. 2026 Oxidative stress is an imbalance between highly reactive molecules produced in cells and antioxidants (such as vitamin C). Julie Scott, Verywell Health, 31 Jan. 2026 Researchers first synthesized the molecule by applying an electric discharge to a substance called thiophenol — a foul-smelling liquid containing sulfur, carbon and hydrogen. Jacopo Prisco, CNN Money, 30 Jan. 2026 Astrocytes appear to keep track of people’s increasing sleep debt throughout the day, likely through a buildup of calcium, and secrete sleep-inducing molecules that alter brain activity. Ingrid Wickelgren, Quanta Magazine, 30 Jan. 2026 See All Example Sentences for molecule

Word History

Etymology

French molécule, from New Latin molecula, diminutive of Latin moles mass

First Known Use

1701, in the meaning defined at sense 1

Time Traveler
The first known use of molecule was in 1701

Browse Nearby Words

Cite this Entry

“Molecule.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/molecule. Accessed 4 Feb. 2026.

Kids Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
1
: the smallest particle of a substance having all the characteristics of the substance
a molecule of water
a molecule of oxygen
2
: a very small bit : particle

Medical Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
: the smallest particle of a substance that retains all the properties of the substance and is composed of one or more atoms

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