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molecule

noun

mol·​e·​cule ˈmä-li-ˌkyül How to pronounce molecule (audio)
1
: the smallest particle of a substance that retains all the properties (see property sense 1a) of the substance and is composed of one or more atoms (see atom sense 1a)
a molecule of water
a molecule of oxygen
2
: a tiny bit : particle
There is a molecule of evidence to support these charges.

Examples of molecule in a Sentence

There is not a molecule of evidence to support these charges. not a molecule of sense in that girl
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
What’s more, this innovation has been achieved without the use of new chemicals but through the use of polymer molecules folded in space. Christopher McFadden, Interesting Engineering, 29 Nov. 2025 Purple carrots, for example, have been shown to have the highest antioxidant activity due to their high concentration of phenolic compounds,3 which are naturally occurring plant molecules with antioxidant and anti-inflammatory properties. Emily Brown, Verywell Health, 28 Nov. 2025 AlphaFold 3, for instance, predicts not just protein structures but several critical aspects of how proteins bind with one another and with small molecules. Jeremy Kahn, Fortune, 28 Nov. 2025 Be thankful for the atoms and molecules that have assembled to make you. Big Think, 27 Nov. 2025 See All Example Sentences for molecule

Word History

Etymology

French molécule, from New Latin molecula, diminutive of Latin moles mass

First Known Use

1701, in the meaning defined at sense 1

Time Traveler
The first known use of molecule was in 1701

Browse Nearby Words

Cite this Entry

“Molecule.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/molecule. Accessed 1 Dec. 2025.

Kids Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
1
: the smallest particle of a substance having all the characteristics of the substance
a molecule of water
a molecule of oxygen
2
: a very small bit : particle

Medical Definition

molecule

noun
mol·​e·​cule ˈmäl-i-ˌkyü(ə)l How to pronounce molecule (audio)
: the smallest particle of a substance that retains all the properties of the substance and is composed of one or more atoms

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