antagonistic

adjective

an·​tag·​o·​nis·​tic (ˌ)an-ˌta-gə-ˈni-stik 

: showing dislike or opposition : marked by or resulting from antagonism

an antagonistic relationship

factions antagonistic to one another

antagonistically

(ˌ)an-ˌta-gə-ˈni-sti-k(ə-)lē 

adverb

Synonyms of antagonistic

• hostile
• negative

Examples of antagonistic in a Sentence

They found it impossible to deal with such antagonistic groups.

countries that have been antagonistic towards each other for centuries

Recent Examples on the Web

When Meloni came into office as the leader of a political party with post-fascist roots, she had been expected to be antagonistic toward Europe and extreme in her views on foreign policy. — ABC News, 13 Aug. 2026

African-American architecture is usually in environments antagonistic to their existence or contributions. — Kamal Morgan, Fort Worth Star-Telegram, 11 Aug. 2026

The long-time TV veteran maintained a recurring part as dominatrix Lady Heather in six episodes of CSI from 2001 to 2011 and later booked another meaty antagonistic role on Nikita. — Kevin Jacobsen, Entertainment Weekly, 5 Aug. 2026

The continued division of Korea into two antagonistic states underscores the limits of land power. — David A. Deptula, Forbes.com, 22 July 2026

Word History

Etymology

see antagonize

First Known Use

circa 1637, in the meaning defined above

Rhymes for antagonistic

• anachronistic
• animalistic
• antiphlogistic
• behavioristic
• cannibalistic
• capitalistic
• characteristic
• collectivistic
• deterministic
• ethnolinguistic
• expressionistic
• idealistic

Kids Definition

antagonistic

adjective

an·​tag·​o·​nis·​tic (ˌ)an-ˌtag-ə-ˈnis-tik 

: showing antagonism

antagonistically

-ti-k(ə-)lē 

adverb

Medical Definition

antagonistic

adjective

an·​tag·​o·​nis·​tic (ˌ)an-ˌtag-ə-ˈnis-tik 

1

: characterized by or resulting from antagonism

antagonistic antibiotics

2

: relating to or being muscles that are antagonists

skeletal muscles arranged in antagonistic pairs

antagonistically

-ti-k(ə-)lē 

adverb