as in to wear
to use up all the physical energy of
the rescue workers pressed on, though their efforts to reach the miners had almost completely fatigued them
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1
as in exhaustion
a complete depletion of energy or strength
the day-long battle against the blaze left firefighters in a state of utter fatigue
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2
as in effort
very hard or unpleasant work
although he had joined the army for action and adventure, much of his day seemed to be devoted to mindless fatigues
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Merriam-Webster unabridged
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