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1
to diminish the physical strength of<several days of hardship in the desert had weakened them>Synonymsdebilitate, enervate, enfeeble, prostrate, sap, soften, tire, wasteRelated Wordscripple, disable, incapacitate; deplete, depress, exhaust, impoverish, unman, wash out; damage, harm, hurt, impair, injure; break down, wear out; paralyzeNear Antonymsenergize, invigorate, vitalize; harden, season, toughenAntonymsbeef (up), fortify, recruit, strengthen
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to lose bodily strength or vigor<the bodybuilder weakened once she eased off on her workouts>Synonymsdecay, droop, fail, flag, go, lag, languish, sag, waste (away), wiltRelated Wordsbreak down, wear out; yieldNear Antonymsconvalesce, recover, recuperate; gain
2
to alter (something) for the worse with the addition of foreign or lower-grade substances<weakened the juice with too much water>— see adulterate
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