1
as in to strengthen
to increase the ability of (as a muscle) to exert physical force
weight lifting will help toughen those flabby muscles of yours
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2
as in to harden
to make able to withstand physical hardship, strain, or exposure
hiking every morning through snow and ice toughened him considerably
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3
as in to stiffen
to make more harsh, uncompromising, or severe
attempts to toughen conditions under which waivers from military service would be permitted
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Merriam-Webster unabridged
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