Synonyms of debilitate

debilitate

verb

di-ˈbi-lə-ˌtāt 

as in to weaken

to diminish the physical strength of

the heart surgery debilitated the college athlete beyond his worst fears

Synonyms & Similar Words

• weaken
• soften
• injure
• hurt
• waste
• paralyze
• exhaust
• enfeeble
• enervate
• cripple
• sap
• tire
• damage
• impair
• devitalize
• incapacitate
• deplete
• depress
• prostrate
• disable
• impoverish
• etiolate
• harm
• hamstring
• invalid
• grind (down)
• lay up
• unman
• wash out
• wear out
• wear down
• break down

Antonyms & Near Antonyms

• strengthen
• fortify
• energize
• recruit
• invigorate
• beef (up)
• rejuvenate
• harden
• season
• vitalize
• toughen

Synonym Chooser

How is the word debilitate distinct from other similar verbs?

Some common synonyms of debilitate are cripple, disable, enfeeble, sap, undermine, and weaken. While all these words mean "to lose or cause to lose strength or vigor," debilitate suggests a less marked or more temporary impairment of strength or vitality.

the debilitating effects of surgery

When is cripple a more appropriate choice than debilitate?

The words cripple and debilitate can be used in similar contexts, but cripple implies causing a serious loss of functioning power through damaging or removing an essential part or element.

crippled by arthritis

Where would disable be a reasonable alternative to debilitate?

While in some cases nearly identical to debilitate, disable suggests bringing about impairment or limitation in a physical or mental ability.

disabled by an injury sustained at work

When would enfeeble be a good substitute for debilitate?

Although the words enfeeble and debilitate have much in common, enfeeble implies a condition of marked weakness and helplessness.

enfeebled by starvation

How are the words undermine and sap related as synonyms of debilitate?

Both undermine and sap suggest a weakening by something working surreptitiously and insidiously.

a poor diet undermines your health

drugs had sapped his ability to think

When is it sensible to use weaken instead of debilitate?

While the synonyms weaken and debilitate are close in meaning, weaken may imply loss of physical strength, health, soundness, or stability or of quality, intensity, or effective power.

a disease that weakens the body's defenses

Example Sentences

Recent Examples of debilitate

This phase can last for several days and can be debilitating, with vomiting and dry heaving up to five times an hour and requiring emergency room visits. —Miriam Fauzia, Dallas Morning News, 4 Feb. 2026

And people with debilitating conditions aren’t necessarily expecting a miracle drug, said the anonymous Reddit user. —Sara Talpos — Undark, STAT, 3 Feb. 2026

Gibson was in and out of doctors’ offices for the next many months without a formal diagnosis — all while continuing to experience her painful and debilitating symptoms. —Toria Sheffield, PEOPLE, 31 Jan. 2026

Successful companies, Swedish celebrities and entrepreneurs fled to free economies across the world to escape debilitating taxes and regulations. —William Z. Fox, Baltimore Sun, 19 Jan. 2026

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