Synonyms of irritation

irritation

noun

ˌir-ə-ˈtā-shən 

as in frustration

the feeling of impatience or anger caused by another's repeated disagreeable acts

Dad's general irritation at the incessant complaining coming from the back seat of the car

Synonyms & Similar Words

• frustration
• exasperation
• annoyance
• displeasure
• grief
• discomfort
• anger
• aggravation
• vexation
• indignation
• irritability
• bother
• trouble
• agitation
• distress
• pip
• upset
• outrage
• resentment
• botheration
• disturbance
• aggro
• perturbation
• pique
• irritableness
• pet
• ire
• umbrage
• angriness
• dander
• dudgeon
• snappishness
• gall
• peeve
• huff
• chafe
• irateness

Antonyms & Near Antonyms

• pleasure
• delight

Example Sentences

Recent Examples of irritation

Mangia said that healthcare providers saw residents with mostly respiratory issues but that many of the residents were also exhibiting rashes and skin irritations. — Los Angeles Times, 20 Aug. 2026

Hair loss and skin irritation during her time managing social at Huda Beauty in Dubai turned out to be caused by water quality, not product routine, an insight that would take years to translate into a viable brand. — Ritu Upadhyay, Footwear News, 19 Aug. 2026

The $26 hydrating cream gave her softer, clearer skin with zero irritation, and reduced mature shoppers’s fine lines. — Kaelin Dodge, InStyle, 19 Aug. 2026

For those prone to irritation, this separates the two ingredients while still providing benefits from both. — Kelsey Stewart, Allure, 18 Aug. 2026