irritation

noun

ir·​ri·​ta·​tion ˌir-ə-ˈtā-shən 

1

a

: the state of being irritated

b

: something that irritates

c

: the act of irritating

2

: a condition of irritability, soreness, roughness, or inflammation of a bodily part

Synonyms

• aggravation
• aggro [British]
• annoyance
• bother
• botheration
• exasperation
• frustration
• grief
• pip [chiefly British]
• vexation

Examples of irritation in a Sentence

Dad's general irritation at the incessant complaining coming from the back seat of the car.

Recent Examples on the Web

Moreover, over 70% of participants experienced mild skin irritation from the vinegar. —Amy Brownstein, Ms, Rdn, Verywell Health, 25 Apr. 2025

These shifts can have a significant impact on the skin barrier, often leading to irritation, dryness, or breakouts. —Cierra Black, Essence, 23 Apr. 2025

While newer formulations tend to avoid these ingredients, some still include actives that can be harsh, especially on sensitive areas like the underarms, where skin is thinner and prone to irritation or darkening. —Tiana Randall, Forbes.com, 22 Apr. 2025

Plus, this formula is fragrance-free to minimize the risk of irritation and is approved by both the National Rosacea Society and the National Eczema Association. —Rebecca Shinners, Glamour, 22 Apr. 2025

Word History

First Known Use

15th century, in the meaning defined at sense 1c

Rhymes for irritation

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

irritation

noun

ir·​ri·​ta·​tion ˌir-ə-ˈtā-shən 

1

: the act of irritating : the state of being irritated

2

: irritant entry 2

Medical Definition

irritation

noun

ir·​ri·​ta·​tion ˌir-ə-ˈtā-shən 

1

a

: the act of irritating

b

: something that irritates

c

: the state of being irritated

2

: a condition of irritability, soreness, roughness, or inflammation of a bodily part