irritation

noun

ir·​ri·​ta·​tion ˌir-ə-ˈtā-shən 

1

a

: the state of being irritated

b

: something that irritates

c

: the act of irritating

2

: a condition of irritability, soreness, roughness, or inflammation of a bodily part

Synonyms of irritation

• frustration
• exasperation
• annoyance
• displeasure
• grief

Examples of irritation in a Sentence

Dad's general irritation at the incessant complaining coming from the back seat of the car.

Recent Examples on the Web

Capricorn December 22 – January 19 Your routine may get disrupted today, and your first reaction could be irritation. — Tarot.com, Hartford Courant, 28 Oct. 2026

Studies have found oil wells can emit carcinogens and are linked to adverse health effects including respiratory issues, headaches, throat irritation and other problems. — Los Angeles Times, 28 Oct. 2026

Some potential reactions include redness, stinging, itching, or irritation. — Taylor Lane, Flow Space, 28 Oct. 2026

In addition, some formulas contain propylene glycol, a humectant that helps sunscreens absorb into the skin but can trigger skin irritation in certain individuals. — Christa Joanna Lee, Allure, 28 Oct. 2026

Word History

First Known Use

15th century, in the meaning defined at sense 1c

Rhymes for irritation

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

irritation

noun

ir·​ri·​ta·​tion ˌir-ə-ˈtā-shən 

1

: the act of irritating : the state of being irritated

2

: irritant entry 2

Medical Definition

irritation

noun

ir·​ri·​ta·​tion ˌir-ə-ˈtā-shən 

1

a

: the act of irritating

b

: something that irritates

c

: the state of being irritated

2

: a condition of irritability, soreness, roughness, or inflammation of a bodily part