irritability

noun

ir·​ri·​ta·​bil·​i·​ty ˌir-ə-tə-ˈbi-lə-tē 

plural irritabilities

1

: the quality or state of being irritable: such as

a

: quick excitability to annoyance, impatience, or anger : petulance

b

: abnormal or excessive excitability of an organ or part of the body

2

: the property of protoplasm and of living organisms that permits them to react to stimuli

Synonyms of irritability

• irritableness
• aggression
• aggressiveness
• anger
• crankiness
• sensitivity
• peevishness
• grouchiness
• crossness
• petulance
• hostility
• irascibility
• indignation
• grumpiness
• testiness

Examples of irritability in a Sentence

the librarian's well-known irritability makes students hesitant to ask questions

Recent Examples on the Web

To counter the irritability, try expressing silent gratitude. —Jennifer Moss, CNBC, 10 Dec. 2025

The mind collapses into repetitive loops of thought and behavior, like procrastination or irritability, that may promise safety in the moment but over time drain creativity and the capacity to thrive. —Jon Rosemberg, Fortune, 9 Dec. 2025

But for women in perimenopause, alcohol can exacerbate the symptoms that come with hormonal fluctuations — like mood swings and irritability, says Christmas, who directs the Menopause Program and Center for Women's Integrated Health at the University of Chicago. —Maria Godoy, NPR, 8 Dec. 2025

While symptoms of menopause such as irritability, mood swings and insomnia are well documented, there is also a heightened risk of depression and anxiety, as recent studies show. —Sashikala Vp, CNN Money, 4 Dec. 2025

Word History

First Known Use

1755, in the meaning defined at sense 2

Rhymes for irritability

• acceptability
• accessibility
• adaptability
• admissibility
• advisability
• affordability
• allowability
• amenability
• amiability
• appealability
• applicability
• availability

Kids Definition

irritability

noun

ir·​ri·​ta·​bil·​i·​ty ˌir-ət-ə-ˈbil-ət-ē 

plural irritabilities

1

: the quality or state of being irritable

especially : readiness to become annoyed or angry

2

: the property of living tissue and living things that permits them to react to stimuli

Medical Definition

irritability

noun

ir·​ri·​ta·​bil·​i·​ty ˌir-ət-ə-ˈbil-ət-ē 

plural irritabilities

1

: the property of protoplasm and of living organisms that permits them to react to stimuli

2

a

: quick excitability to annoyance, impatience, or anger

b

: abnormal or excessive excitability of an organ or part of the body (as the stomach or bladder)