Synonyms of de novo

de novo

adverb

di-ˈnō-(ˌ)vō 

as in again

yet another time

since a mistrial was declared, the case will have to be tried de novo

Synonyms & Similar Words

• again
• anew
• constantly
• over
• invariably
• afresh
• often
• repeatedly
• continuously
• consistently
• frequently
• ever
• always
• continually
• forever
• incessantly
• freshly
• newly
• perpetually
• oft
• endlessly
• unfailingly
• evermore
• oftentimes
• recurrently

Antonyms & Near Antonyms

• never
• ne'er
• rarely
• seldom
• little
• sometimes
• unusually
• infrequently
• nevermore
• occasionally
• intermittently
• periodically
• sporadically

Example Sentences

Recent Examples of de novo

The vast majority of AI devices go to market through the FDA’s 510(k) clearance pathway; fewer than 10 each year receive de novo classification, which typically requires more clinical evidence. — Katie Palmer, STAT, 11 Sep. 2026

Kalver had de novo metastatic breast cancer, meaning the disease had spread beyond the breast and nearby lymph nodes to to distant areas of the body, before it was first diagnosed. — Emily Cegielski, Flow Space, 24 Aug. 2026

By contrast, government lawyers demanding payment of an FCC fine must prove to a jury in a de novo trial that the company violated the law. — ArsTechnica, 4 June 2026

The partnership, which includes licensing, co-development, and co-commercialization opportunities across a diverse portfolio of antibody-drug conjugates, will involve the research and development of 12 breakthrough early-stage and de novo cancer medicines, the company said in a filing. — Justina Lee, CNBC, 29 May 2026

In 2025, the OCC reported 14 de novo charter applications, several tied to novel and digital-asset activity. — Frank Sorrentino, Forbes.com, 23 Jan. 2026

Because this technology is new, PreEvnt is pursuing a de novo pathway, which allows devices to be evaluated while standards are still being defined. — Kurt Knutsson, FOXNews.com, 17 Jan. 2026

The agency signed off on de novo charters for Circle and Ripple, while approving conversions from state trust companies to national trust banks for BitGo, Fidelity and Paxos. — Julia Shapero, The Hill, 12 Dec. 2025

Without discussion, the council unanimously decided against a de novo hearing, which upholds the Planning Department’s decision to mark the application incomplete. — Luke Harold, San Diego Union-Tribune, 26 Sep. 2025