Medical Dictionary

mischarge

play
transitive verb mis·charge \ ˌmis-ˈchärj \

medical Definition of mischarge

mischarged; mischarging
:to attach an incorrect amino acid to during protein synthesis
  • Benzer and coworkers showed in 1962 that cysteine tRNA mischarged with alanine (Ala-tRNACys) delivers alanine to growing polypeptide chains in vitro in response to cysteine codons.
  • —David A. Tirrell, in Physical Biology: From Atoms to Science2008

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