HIV

noun

ˌāch-ˌī-ˈvē 

1

: either of two retroviruses (species Human immunodeficiency virus 1 and 2 of the genus Lentivirus) that infect and destroy helper T cells of the immune system and that when left untreated cause AIDS

Note: HIV retroviruses are transmitted through contact with blood, semen, rectal and vaginal fluids, or breast milk and typically cause flu-like symptoms during the acute phase of infection, but often cause few or no symptoms during the chronic phase of infection when treated with antiretroviral drugs.

… the longer people are infected with HIV and the more immune-deficient they become, the more readily they seem to pass HIV to others.

—Robert R. Redfield et al.

Years of careful research have proven beyond doubt that the HIV virus causes AIDS, that antiretroviral drug treatment saves lives, and that the drug nevirapine is safe and effective in preventing the spread of HIV from mothers to their babies.

—Richard Marlink et al.

called also AIDS virus, human immunodeficiency virus

compare hiv-1, hiv-2

2

: the infection or disease caused by HIV

Early symptoms of HIV develop in 50 to 90 percent of people who are infected, usually beginning two to four weeks after exposure. … Because the signs and symptoms of … HIV may be similar to other common illnesses, such as mononucleosis, most people do not initially realize that they have HIV.

—Paul E. Sax

Examples of HIV in a Sentence

Recent Examples on the Web

The work has garnered bipartisan support: in 2018, during President Trump’s first term, the PEPFAR Extension Act of 2018 provided support to fight HIV/AIDS, tuberculosis, and malaria through 2023. —Kelly Phillips Erb, Forbes.com, 12 June 2025

That includes canceling $500 million for activities related to infectious diseases and child and maternal health and another $400 million to address the global HIV epidemic. —Kevin Freking, Los Angeles Times, 12 June 2025

Seven hundred thousand dead—disproportionately poor, unhoused, and people of color—from HIV/AIDS. —Marcos Gonsalez, Time, 12 June 2025

STIs can also lead to infertility and a higher risk of cancer as well HIV infection, according to the American Society for Microbiology. —Emma Hall, Sacbee.com, 12 June 2025

Word History

First Known Use

1986, in the meaning defined at sense 1

Phrases Containing HIV

• anti-HIV

Kids Definition

HIV

noun

ˌāch-ˌī-ˈvē 

: any of a group of viruses that infect and destroy helper T cells causing the marked reduction in their numbers that is diagnostic of AIDS

Medical Definition

HIV

noun

ˌā-ˌchī-ˈvē 

1

: either of two retroviruses (species Human immunodeficiency virus 1 and 2 of the genus Lentivirus) that infect and destroy helper T cells of the immune system and that when left untreated cause AIDS

Note: HIV retroviruses are transmitted through contact with blood, semen, rectal and vaginal fluids, or breast milk and typically cause flu-like symptoms during the acute phase of infection, but often cause few or no symptoms during the chronic phase of infection when treated with antiretroviral drugs.

called also AIDS virus, human immunodeficiency virus

compare hiv-1, hiv-2

2

: the infection or disease caused by HIV