HIV

noun

ˌāch-ˌī-ˈvē 

1

: either of two retroviruses (Lentivirus humimdef1 and L. humimdef2) that infect and destroy helper T cells of the immune system and that when left untreated cause AIDS

Note: HIV retroviruses are transmitted through contact with blood, semen, rectal and vaginal fluids, or breast milk and typically cause flu-like symptoms during the acute phase of infection, but often cause few or no symptoms during the chronic phase of infection when treated with antiretroviral drugs.

… the longer people are infected with HIV and the more immune-deficient they become, the more readily they seem to pass HIV to others.

—Robert R. Redfield et al.

Years of careful research have proven beyond doubt that the HIV virus causes AIDS, that antiretroviral drug treatment saves lives, and that the drug nevirapine is safe and effective in preventing the spread of HIV from mothers to their babies.

—Richard Marlink et al.

called also AIDS virus, human immunodeficiency virus

see also hiv-1, hiv-2

2

: the infection or disease caused by HIV

Early symptoms of HIV develop in 50 to 90 percent of people who are infected, usually beginning two to four weeks after exposure. … Because the signs and symptoms of … HIV may be similar to other common illnesses, such as mononucleosis, most people do not initially realize that they have HIV.

—Paul E. Sax

Examples of HIV in a Sentence

Recent Examples on the Web

Recall those hundred or so volunteers who put their own bodies on the line to advance the possibility—absolutely not the certainty—of eliminating a brutal scourge, HIV/AIDS. —Literary Hub, 11 June 2026

As a social worker assisting survivors of domestic violence and patients facing HIV and AIDS diagnoses, Renee Duxler saw first-hand how people’s lives can be shaped for better or worse by policy decisions and budget allocations. —Matthew Kelly, Kansas City Star, 10 June 2026

Those lawsuits include other detainees who say they were denied medication or had treatment delayed for conditions including cancer, high blood pressure, epilepsy, Parkinson's, HIV, diabetes, infections, depression and more. —CBS News, 9 June 2026

Larger clinical trials are needed to confirm the findings, determine how long treatment effects last and establish optimal dosing and treatment duration both for people with HIV and the broader population. —Ashley MacKin Solomon, San Diego Union-Tribune, 9 June 2026

Word History

First Known Use

1986, in the meaning defined at sense 1

Phrases Containing HIV

• anti-HIV

Kids Definition

HIV

noun

ˌāch-ˌī-ˈvē 

: any of a group of viruses that infect and destroy helper T cells causing the marked reduction in their numbers that is diagnostic of AIDS

Medical Definition

HIV

noun

ˌā-ˌchī-ˈvē 

1

: either of two retroviruses (Lentivirus humimdef1 and L. humimdef2) that infect and destroy helper T cells of the immune system and that when left untreated cause AIDS

Note: HIV retroviruses are transmitted through contact with blood, semen, rectal and vaginal fluids, or breast milk and typically cause flu-like symptoms during the acute phase of infection, but often cause few or no symptoms during the chronic phase of infection when treated with antiretroviral drugs.

called also AIDS virus, human immunodeficiency virus

see also hiv-1, hiv-2

2

: the infection or disease caused by HIV