nevirapine

noun

ne·​vi·​ra·​pine nə-ˈvir-ə-ˌpēn  -ˈvī-rə- 

: an antiretroviral drug C₁₅H₁₄N₄O that inhibits reverse transcriptase and is administered orally in combination with at least one other antiretroviral in the treatment of HIV-1 infection

Example Sentences

Recent Examples on the Web

As a result, many babies were born with nevirapine-resistant forms of the virus, and the efficacy of pediatric Triomune fell by about half, Dr. Pécoul said. New York Times, 29 Nov. 2019

The prevalence of resistance in people who restarted efavirenz and nevirapine after interrupting treatment was much higher (21%) than in first-time users (8%). Scientific American, 30 July 2019

The three drugs in question—stavudine, lamivudine, and nevirapine—were made by three different multinational drug companies. Katherine Eban, Quartz India, 15 July 2019

Five years later, a study in Uganda showed a single dose of another ARV, nevirapine, given to a mother in labor and a baby at birth, could reduce transmission by 50%, which soon became a standard of care. Jon Cohen, Science | AAAS, 12 June 2018

Word History

Etymology

perhaps from ne- (by reversal of enzyme) + viral + dipyridodiazepinone, class of drugs to which nevirapine belongs

First Known Use

1991, in the meaning defined above

Medical Definition

nevirapine

noun

ne·​vi·​ra·​pine nə-ˈvir-ə-ˌpēn  -ˈvī-rə- 

: a reverse transcriptase inhibitor C₁₅H₁₄N₄O that is administered orally in combination with at least one other antiretroviral agent in the treatment of HIV-1 infection