: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases (see base entry 1 sense 6b) which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei compare recombinant dna

Illustration of DNA

Illustration of dna
  • A molecular model
  • 1 hydrogen
  • 2 oxygen
  • 3 carbon in the helical phosphate ester chains
  • 4 carbon and nitrogen in the cross-linked purine and pyrimidine bases
  • 5 phosphorus
  • B double helix

Examples of DNA in a Sentence

Recent Examples on the Web
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Fortunately, today, researchers explained that recent advancements in paleogenomics have permitted this cross-examination between modern genomes and ancient DNA, Archaeology Mag reports. Maria Mocerino, Interesting Engineering, 21 Dec. 2025 These SAPs occur because of a variation in an individual's DNA code, specifically a non-synonymous single nucleotide polymorphism, which changes one amino acid in the protein chain. Abhimanyu Ghoshal, New Atlas, 20 Dec. 2025 Additionally, a rapid DNA test of the remains of Neves Valente shows a preliminary match to DNA recovered from the Brown crime scene, according to the FBI. Aaron Katersky, ABC News, 19 Dec. 2025 As with the regular production model, the Cento exudes the yard’s elegant design DNA, with a sporty character, sleek, flowing lines, the classic mahogany deck, and gleaming steel accents. Rachel Cormack, Robb Report, 18 Dec. 2025 See All Example Sentences for DNA

Word History

Etymology

deoxyribonucleic acid

First Known Use

1944, in the meaning defined above

Time Traveler
The first known use of DNA was in 1944

Browse Nearby Words

Cite this Entry

“DNA.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/DNA. Accessed 21 Dec. 2025.

Kids Definition

: any of various nucleic acids that are located especially in cell nuclei, are usually the chemical basis of heredity, and are composed of two nucleotide chains held together by hydrogen bonds in a pattern resembling a flexible twisted ladder compare rna

Medical Definition

: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei

called also deoxyribonucleic acid

see recombinant dna

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