tissue

noun

tis·​sue ˈti-(ˌ)shü 

 chiefly British  ˈtis-(ˌ)yü

1

: a piece of soft absorbent tissue paper used especially as a handkerchief or for removing cosmetics

2

: an aggregate of cells usually of a particular kind together with their intercellular substance that form one of the structural materials of a plant or an animal

3

a

: a fine lightweight often sheer fabric

b

: mesh, network, web

a tissue of lies

tissuey

ˈti-shə-wē 

adjective

Examples of tissue in a Sentence

She wiped her nose with a tissue.

a sample of brain tissue

The drug can damage the body's tissues.

a box wrapped in tissue

Recent Examples on the Web

Scientists were able to prepare soft tissue remains while also protecting them, and when hit with ultraviolet light, the tissue glowed. —Greg Wehner, FOXNews.com, 15 May 2025

Smith subsequently contracted sepsis – a life-threatening response by the body to infection that can lead to tissue damage, organ failure and death – and nearly had to have his leg amputated. —Ben Church, CNN Money, 14 May 2025

But with rapid weight loss comes a depletion of facial volume and descent of tissues. —Nadja Sayej, Forbes.com, 13 May 2025

To use the Teal Wand, patients request a self-collection kit online from Teal Health, ask their healthcare provider to prescribe the test, then collect tissue samples in the privacy of their own home. —Lisa Rapaport, EverydayHealth.com, 12 May 2025

Word History

Etymology

Middle English tysshewe, tyssew, a rich fabric, from Anglo-French tissue, from past participle of tistre to weave, from Latin texere — more at technical

First Known Use

1563, in the meaning defined at sense 3a

Phrases Containing tissue

• adipose tissue
• bathroom tissue
• connective tissue
• granulation tissue
• permanent tissue
• scar tissue
• tissue culture
• tissue fluid
• tissue of lies
• tissue paper
• tissue plasminogen activator
• vascular tissue
• woven a tissue of lies

Rhymes for tissue

• blew
• blue
• boo
• brew
• chew
• chou
• clue
• coo
• coup
• crew
• cue
• dew

Kids Definition

tissue

noun

tis·​sue ˈtish-ü 

1

: a fine lightweight fabric

2

: a piece of soft absorbent paper

3

: a mass or layer of cells usually of one kind together with the uniting or enclosing substance around and between them that form the basic structural materials of a plant or an animal compare connective tissue

Medical Definition

tissue

noun

tis·​sue

ˈtish-(ˌ)ü, ˈtish-ə(-w), chiefly British ˈtis-(ˌ)yü

: an aggregate of cells usually of a particular kind together with their intercellular substance that form one of the structural materials of a plant or an animal and that in animals include connective tissue, epithelium, muscle tissue, and nerve tissue