tissue

noun

tis·​sue ˈti-(ˌ)shü 

chiefly British ˈtis-(ˌ)yü

1

: a piece of soft absorbent tissue paper used especially as a handkerchief or for removing cosmetics

2

: an aggregate of cells usually of a particular kind together with their intercellular substance that form one of the structural materials of a plant or an animal

3

a

: a fine lightweight often sheer fabric

b

: mesh, network, web

a tissue of lies

tissuey

ˈti-shə-wē 

adjective

Examples of tissue in a Sentence

She wiped her nose with a tissue.

a sample of brain tissue

The drug can damage the body's tissues.

a box wrapped in tissue

Recent Examples on the Web

Renal infarction is when the flow of blood to your kidney gets blocked, leading to the death of kidney tissue. — Bruce Y. Lee, Forbes.com, 8 Aug. 2026

Greenlaw, of course, spent much of his one year in Denver in 2025 working through soft-tissue injuries, before being cut and signing back to the San Francisco 49ers this offseason. — Luca Evans, Denver Post, 7 Aug. 2026

Proteins are made of amino acids and are needed to build and repair tissues and make important compounds like enzymes and hormones. — Jillian Kubala, HEALTH, 7 Aug. 2026

The discomfort usually lasts only a few seconds to a few minutes and typically resolves as the tissues warm up. — Encyclopedia Britannica, 7 Aug. 2026

Word History

Etymology

Middle English tysshewe, tyssew, a rich fabric, from Anglo-French tissue, from past participle of tistre to weave, from Latin texere — more at technical

First Known Use

1563, in the meaning defined at sense 3a

Phrases Containing tissue

• adipose tissue
• bathroom tissue
• connective tissue
• granulation tissue
• permanent tissue
• scar tissue
• tissue culture
• tissue fluid
• tissue of lies
• tissue paper
• tissue plasminogen activator
• vascular tissue
• woven a tissue of lies

Rhymes for tissue

• blew
• blue
• boo
• brew
• chew
• chou
• clue
• coo
• coup
• crew
• cue
• dew

Kids Definition

tissue

noun

tis·​sue ˈtish-ü 

1

: a fine lightweight fabric

2

: a piece of soft absorbent paper

3

: a mass or layer of cells usually of one kind together with the uniting or enclosing substance around and between them that form the basic structural materials of a plant or an animal compare connective tissue

Medical Definition

tissue

noun

tis·​sue

ˈtish-(ˌ)ü, ˈtish-ə(-w), chiefly British ˈtis-(ˌ)yü

: an aggregate of cells usually of a particular kind together with their intercellular substance that form one of the structural materials of a plant or an animal and that in animals include connective tissue, epithelium, muscle tissue, and nerve tissue