tissue plasminogen activator

noun

Definition of tissue plasminogen activator

: a clot-dissolving enzyme with an affinity for fibrin that is produced naturally in blood vessel linings and is used in a genetically engineered form to prevent damage to heart muscle following a heart attack and reduce neurological damage following ischemic stroke —abbreviation TPA

Examples of tissue plasminogen activator in a Sentence

Recent Examples on the Web To facilitate protein expression of the RBD antigen, a CMV promoter and human tissue plasminogen activator (tPA) were also inserted, as shown in the figure below. — William A. Haseltine, Forbes, 31 Jan. 2022 The procedure was now too risky and he was given intravenous tissue plasminogen activators (TPA), a treatment used to help dissolve blood clots. — Hannah Drown, cleveland, 31 Oct. 2019 To qualify, hospitals must meet quality measures developed to reduce the time between the patient’s arrival at the hospital and treatment with the clot-buster tissue plasminogen activator, or tPA. — baltimoresun.com/maryland/carroll, 19 Aug. 2019 The drug, known as tissue plasminogen activator (tPA), is a potent blood thinner and was approved as an effective clot-busting treatment by the Food and Drug Administration in 1996. — Kevin Sheth, Washington Post, 8 Apr. 2018 For stroke, tissue plasminogen activator (tPA) must be administered within three hours to dissolve blood clots that may be blocking blood flow to the brain. — Bryant Stamford, The Courier-Journal, 29 Mar. 2018 To qualify for the Target: Stroke Honor Roll, hospitals must meet quality measures developed to reduce the time between the patient's arrival at the hospital and treatment with the clot-busting agent called tissue plasminogen activator, or tPA. — Houston Chronicle, 31 Oct. 2017 See More

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“Tissue plasminogen activator.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/tissue%20plasminogen%20activator. Accessed 11 Aug. 2022.

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tissue plasminogen activator

noun

Medical Definition of tissue plasminogen activator

: a clot-dissolving enzyme that has an affinity for fibrin, that catalyzes the conversion of plasminogen to plasmin, that is produced naturally in blood vessel linings, and that is used in a genetically engineered form to prevent damage to heart muscle following a heart attack and to reduce neurological damage following ischemic stroke —abbreviation tPA