tissue plasminogen activator

noun

Definition of tissue plasminogen activator

:a clot-dissolving enzyme with an affinity for fibrin that is produced naturally in blood vessel linings and is used in a genetically engineered form to prevent damage to heart muscle following a heart attack and reduce neurological damage following ischemic stroke abbreviation TPA

First Known Use of tissue plasminogen activator

1981


Medical Dictionary

tissue plasminogen activator

noun

medical Definition of tissue plasminogen activator

:a clot-dissolving enzyme that has an affinity for fibrin, that catalyzes the conversion of plasminogen to plasmin, that is produced naturally in blood vessel linings, and that is used in a genetically engineered form to prevent damage to heart muscle following a heart attack and to reduce neurological damage following ischemic stroke abbreviation tPA

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