1
: the inducing of a relaxed easy state especially by the use of sedatives
2
: a state resulting from or as if from sedation

Examples of sedation in a Sentence

For some patients, sedation may be necessary.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Melatonin has more evidence for sleep timing, while L-theanine supports relaxation without causing sedation. — T'keyah Bazin, Verywell Health, 25 Sep. 2026 When to seek medical attention People who use kratom and begin breathing slowly or shallowly, or who become excessively drowsy or difficult to awaken, may be experiencing serious sedation that can interfere with breathing, Steinman said. — Melissa Rudy, FOXNews.com, 23 Sep. 2026 More than a week later, Leah’s care team was able to extubate her and reduce her sedation levels for the first time after a week of life support and multiple surgeries. — Desiree Anello, PEOPLE, 16 Sep. 2026 Orexin antagonists were developed as a treatment for insomnia, differing from conventional sleeping pills that induce sedation. — Harriet Marsden, TheWeek, 20 Aug. 2026 See All Example Sentences for sedation

Word History

First Known Use

1543, in the meaning defined at sense 1

Time Traveler
The first known use of sedation was in 1543

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Cite this Entry

“Sedation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/sedation. Accessed 27 Sep. 2026.

Medical Definition

sedation

noun
1
: the inducing of a relaxed easy state especially by the use of sedatives
2
: a state resulting from sedation see conscious sedation, deep sedation
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