scle·​ro·​sis | \ sklə-ˈrō-səs How to pronounce sclerosis (audio) \

Definition of sclerosis

1 : pathological hardening of tissue especially from overgrowth of fibrous tissue or increase in interstitial tissue also : a disease characterized by sclerosis
2 : an inability or reluctance to adapt or compromise political sclerosis

Examples of sclerosis in a Sentence

Recent Examples on the Web Multiple sclerosis symptoms can worsen when your temperature rises, making body temperature regulation crucial to people who live with the condition. Maggie O'neill,, "7 Cooling Neck Wraps to Help You Regulate Your Body Temperature," 19 June 2020 Biogen has suffered a surprise blow to its blockbuster multiple-sclerosis franchise. Charley Grant, WSJ, "Biogen Can Bounce Back from Multiple-Sclerosis Blow," 18 June 2020 Douthat’s chapters on stagnating innovation and institutional sclerosis as elements of our decadence are more conventional, though informative and well balanced. Mark Lilla, New York Times, "Ross Douthat Has a Vision of America. It’s Grim.," 25 Feb. 2020 Art Day in the Park is an annual commemoration of the life of Cecelia Johnson, who died in 2014 from muscular sclerosis and Ehlers-Danlos syndrome and is held around or on Johnson’s birthday. Samantha Lopez, Houston Chronicle, "Menil Park's annual Art Day celebrates beloved Houston artist who died at 35," 2 Mar. 2020 Tuberous sclerosis complex causes benign tumors in the brain and elsewhere, and epilepsy in more than 80% of patients. Jennifer Couzin-frankel, Science | AAAS, "As epilepsy drugs fail nearly one-third of patients, scientists seek root causes of seizures," 12 Dec. 2019 Her devotion to medicine and saving the sick stems from her sister dying from stomach cancer and her mother succumbing to the ravages of systemic sclerosis. Bill Rankin, ajc, "Why an acclaimed Georgia Tech professor is barred from her COVID-19 research," 19 Mar. 2020 And while there are some new promising signs of veteran political organizing on the left, party sclerosis is handicapping this work. Jasper Craven, The New Republic, "Pete Buttigieg and the Democrats’ Veteran Problem," 11 Feb. 2020 The medicine is the gold standard for treating tuberous sclerosis patients who develop epilepsy. Jennifer Couzin-frankel, Science | AAAS, "As epilepsy drugs fail nearly one-third of patients, scientists seek root causes of seizures," 12 Dec. 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'sclerosis.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of sclerosis

1846, in the meaning defined at sense 1

History and Etymology for sclerosis

Middle English sclirosis tumor, from Medieval Latin, from Greek sklērōsis hardening, from sklēroun to harden, from sklēros

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Time Traveler for sclerosis

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The first known use of sclerosis was in 1846

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Statistics for sclerosis

Last Updated

26 Jun 2020

Cite this Entry

“Sclerosis.” Dictionary, Merriam-Webster, Accessed 12 Jul. 2020.

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More Definitions for sclerosis


How to pronounce sclerosis (audio)

English Language Learners Definition of sclerosis

medical : a disease in which soft parts inside the body (such as arteries or muscles) become hard


scle·​ro·​sis | \ sklə-ˈrō-səs How to pronounce sclerosis (audio) \
plural scleroses\ -​ˌsēz How to pronounce scleroses (audio) \

Medical Definition of sclerosis

1 : a pathological condition in which a tissue has become hard and which is produced by overgrowth of fibrous tissue and other changes (as in arteriosclerosis) or by increase in interstitial tissue and other changes (as in multiple sclerosis)

called also hardening

2 : any of various diseases characterized by sclerosis usually used in combination — see arteriosclerosis, multiple sclerosis, myelosclerosis

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More from Merriam-Webster on sclerosis

Rhyming Dictionary: Words that rhyme with sclerosis

Spanish Central: Translation of sclerosis

Nglish: Translation of sclerosis for Spanish Speakers

Britannica English: Translation of sclerosis for Arabic Speakers Encyclopedia article about sclerosis

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