multiple sclerosis

noun

: a demyelinating disease marked by patches of hardened tissue in the brain or the spinal cord and associated especially with partial or complete paralysis and jerking muscle tremor

Examples of multiple sclerosis in a Sentence

Recent Examples on the Web

March is awareness month for autoimmune disorders, bleed disorders, multiple sclerosis, colorectal cancer, endometriosis, traumatic brain injuries and trisomy, a genetic condition characterized by the presence of three copies of a specific chromosome instead of the usual pair (two copies). —Scott Lafee, San Diego Union-Tribune, 3 Mar. 2026

Bong said while Mary Rasmussen had multiple sclerosis and kept a positive outlook through health challenges, her death was unexpected. —Anna Ortiz, Chicago Tribune, 26 Feb. 2026

The actress, who was diagnosed with multiple sclerosis in 2021, is releasing a memoir called You With the Sad Eyes on March 3. —Jason P. Frank, Vulture, 24 Feb. 2026

In 2018, with Velez by her side, Santiago, who has multiple sclerosis, showed us where the van was last parked in their Jefferson Park neighborhood. —Dave Savini, CBS News, 19 Feb. 2026

Word History

First Known Use

1885, in the meaning defined above

Rhymes for multiple sclerosis

• actinomycosis
• atherosclerosis
• endometriosis
• erythematosus
• erythroblastosis
• granulomatosis
• hemochromatosis
• histiocytosis
• hyperkeratosis
• ketoacidosis
• mononucleosis
• osteonecrosis

Kids Definition

multiple sclerosis

noun

: a disease marked by patches of hardened tissue in the brain or spinal cord resulting in symptoms (as weakness or paralysis in the arms or legs or loss of balance and muscle coordination) that usually come and go

Medical Definition

multiple sclerosis

noun

: a demyelinating disease marked by patches of hardened tissue in the brain or the spinal cord and associated especially with partial or complete paralysis and jerking muscle tremor