hy·​per·​ker·​a·​to·​sis | \ ˌhī-pər-ˌker-ə-ˈtō-səs How to pronounce hyperkeratosis (audio) \
plural hyperkeratoses\ ˌhī-​pər-​ˌker-​ə-​ˈtō-​ˌsēz How to pronounce hyperkeratosis (audio) \

Definition of hyperkeratosis

: hypertrophy of the corneous layer of the skin

Other Words from hyperkeratosis

hyperkeratotic \ ˌhī-​pər-​ˌker-​ə-​ˈtä-​tik How to pronounce hyperkeratosis (audio) \ adjective

Examples of hyperkeratosis in a Sentence

Recent Examples on the Web Not only can weather changes and hyperkeratosis affect your pooch’s paws, but these conditions can affect their noses as well. Nicole Forsyth, The Mercury News, 5 Sep. 2019 Or your dog may have a genetic condition called hyperkeratosis that makes their paws and noses vulnerable to becoming dry. Nicole Forsyth, The Mercury News, 5 Sep. 2019 Soften Up Don’t overlook the rest of your hands: Rough patches on the palms can be remedied using a callus softener like Deborah Lippmann’s Get Off, which uses lactic acid to break down hyperkeratosis (thickening of the skin). Donna Bulseco, WSJ, 2 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'hyperkeratosis.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of hyperkeratosis

1841, in the meaning defined above

History and Etymology for hyperkeratosis

earlier as a name for keratoconus (conical distortion of the cornea), borrowed from New Latin (in a German context), from hyper- hyper- + Greek kerat-, kéras "horn" + New Latin -osis -osis — more at kerato-

Note: As an ophthalmological term introduced by the German ophthalmologist Karl Himly (1772-1837) in Bibliothek für Ophthalmologie, 1. Band, 2. Stück (Hannover, 1819), p. 401.

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The first known use of hyperkeratosis was in 1841

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Cite this Entry

“Hyperkeratosis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hyperkeratosis. Accessed 30 Sep. 2022.

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More Definitions for hyperkeratosis


hy·​per·​ke·​ra·​to·​sis | \ -ˌker-ə-ˈtō-səs How to pronounce hyperkeratosis (audio) \
plural hyperkeratoses\ -​ˈtō-​ˌsēz How to pronounce hyperkeratosis (audio) \

Medical Definition of hyperkeratosis

1 : hypertrophy of the stratum corneum layer of the skin
2a : any of various conditions marked by hyperkeratosis
b : a disease of cattle that is marked by thickening and wrinkling of the hide, by formation of papillary outgrowths on the buccal mucous membranes, and often by a watery discharge from eyes and nose, diarrhea, loss of weight, and abortion of pregnant animals and that is caused especially by ingestion of the chlorinated naphthalene of various lubricating oils, by arsenic poisoning, or by inherited congenital ichthyosis

called also X-disease, XX disease

Other Words from hyperkeratosis

hyperkeratotic \ -​ˈtät-​ik How to pronounce hyperkeratosis (audio) \ adjective

More from Merriam-Webster on hyperkeratosis

Britannica.com: Encyclopedia article about hyperkeratosis


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