hypertrophy

noun
hy·​per·​tro·​phy | \hī-ˈpər-trə-fē \
plural hypertrophies

Definition of hypertrophy 

(Entry 1 of 2)

1 biology : excessive development of an organ or part specifically : increase in bulk (as by thickening of muscle fibers) without multiplication of parts cardiac hypertrophy

2 : exaggerated growth or complexity economic hypertrophy

hypertrophy

verb
hypertrophied; hypertrophying

Definition of hypertrophy (Entry 2 of 2)

intransitive verb

: to undergo hypertrophy (see hypertrophy entry 1) A healthy kidney hypertrophies when the other fails. hypertrophied nationalism

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Other Words from hypertrophy

Noun

hypertrophic \ˌhī-​pər-​ˈtrō-​fik \ adjective

Breaking Down Hypertrophy

When the prefix hyper-, "above, beyond", is joined to -trophy, we get the opposite of atrophy. An organ or part becomes hypertrophic when it grows so extremely that its function is affected. Muscle hypertrophy is common in men who do strength training, and is often harmless; but extreme muscle hypertrophy generally involves taking steroids, which can do great damage to the body. Hypertrophy of the heart sounds as if it might be healthy, but instead it's usually a bad sign. As the example sentence shows, hypertrophy, like atrophy, can be used in nonmedical ways as well.

Examples of hypertrophy in a Sentence

Recent Examples on the Web: Noun

Greater handgrip strength was associated with less cardiac hypertrophy and remodeling, which are indicators of long-term cardiovascular disease. Mark Lieber, CNN, "A strong handshake could indicate a healthy heart," 14 Mar. 2018 Cardiomegaly -- also known as an enlarged heart -- caused his death along with myocyte hypertrophy with hypergranular myocytes and epicarditis, the Cuyahoga County Medical Examiner's Office determined. Evan Macdonald, cleveland.com, "Family of Brush hockey player who died from undiagnosed heart condition provides screenings to athletes," 24 Jan. 2018 For those with more severe hypertension in need of medication, echocardiograms have revealed cardiac complications more usually seen in adults, such as left ventricular hypertrophy, a thickening of the heart muscle. Carrie Arnold, Newsweek, "Heart Disease: Children Are Developing Conditions Tied to Aging—and Pediatricians Are on High Alert," 5 Sep. 2017 Cardiomegaly -- also known as an enlarged heart -- caused the 17-year-old boy's death along with myocyte hypertrophy with hypergranular myocytes and epicarditis, the Cuyahoga County Medical Examiner's Office determined. Evan Macdonald, cleveland.com, "Family of Brush hockey player who died of enlarged heart starts foundation in his honor," 23 Aug. 2017 Cardiomegaly -- also known as an enlarged heart -- caused his death along with myocyte hypertrophy with hypergranular myocytes and epicarditis, records show. Evan Macdonald, cleveland.com, "Enlarged heart caused Brush High School hockey player's unexpected death, autopsy shows," 13 July 2017 In mice, Unity’s treatments delay cancer, prevent cardiac hypertrophy, and increase median life span by thirty-five per cent. Tad Friend, The New Yorker, "Silicon Valley’s Quest to Live Forever," 24 Mar. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'hypertrophy.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of hypertrophy

Noun

1834, in the meaning defined at sense 1

Verb

1883, in the meaning defined above

History and Etymology for hypertrophy

Noun

probably from New Latin hypertrophia, from hyper- + -trophia -trophy

Verb

see hypertrophy entry 1

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The first known use of hypertrophy was in 1834

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More Definitions for hypertrophy

hypertrophy

noun
hy·​per·​tro·​phy | \hī-ˈpər-trə-fē \
plural hypertrophies

Medical Definition of hypertrophy 

(Entry 1 of 2)

: excessive development of an organ or part specifically : increase in bulk (as by thickening of muscle fibers) without multiplication of parts ventricular hypertrophy

hypertrophy

intransitive verb
hypertrophied; hypertrophying

Medical Definition of hypertrophy (Entry 2 of 2)

: to undergo hypertrophy

More from Merriam-Webster on hypertrophy

Britannica.com: Encyclopedia article about hypertrophy

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