cirrhosis

noun

cir·​rho·​sis sə-ˈrō-səs How to pronounce cirrhosis (audio)
plural cirrhoses sə-ˈrō-ˌsēz How to pronounce cirrhosis (audio)
: widespread disruption of normal liver structure by fibrosis and the formation of regenerative nodules that is caused by any of various chronic progressive conditions affecting the liver (such as long-term alcohol abuse or hepatitis)
cirrhotic adjective or noun

Examples of cirrhosis in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
And about 25 percent of them will die from sequelae of that infection either from liver disease, cirrhosis or from liver cancer. CBS News, 7 Dec. 2025 At that stage, the disease raises the risk of liver failure, liver cancer and cirrhosis. Cara Lynn Shultz, PEOPLE, 6 Dec. 2025 The rationale for giving the vaccine right away is to wipe out an infection that will afflict the majority of people who contract it as babies for the rest of their life (and, for as many as a quarter of those chronically infected, result in their death from cirrhosis or liver cancer). Tom Bartlett, The Atlantic, 5 Dec. 2025 What To Know For more than three decades, federal guidelines have advised that every newborn receive a hepatitis B vaccine at birth, part of a strategy adopted in 1991 to curb infections that can lead to chronic liver disease, cancer and cirrhosis. Gabe Whisnant, MSNBC Newsweek, 5 Dec. 2025 See All Example Sentences for cirrhosis

Word History

Etymology

New Latin, from Greek kirrhos orange-colored; akin to Old English hār gray — more at hoar

First Known Use

circa 1847, in the meaning defined above

Time Traveler
The first known use of cirrhosis was circa 1847

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Cite this Entry

“Cirrhosis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cirrhosis. Accessed 12 Dec. 2025.

Kids Definition

cirrhosis

noun
cir·​rho·​sis sə-ˈrō-səs How to pronounce cirrhosis (audio)
: an increase in fiber-containing tissue and hardening of the liver

Medical Definition

cirrhosis

noun
cir·​rho·​sis sə-ˈrō-səs How to pronounce cirrhosis (audio)
plural cirrhoses -ˌsēz How to pronounce cirrhosis (audio)
: widespread disruption of normal liver structure by fibrosis and the formation of regenerative nodules that is caused by any of various chronic progressive conditions affecting the liver (as long-term alcohol abuse or hepatitis) see biliary cirrhosis

More from Merriam-Webster on cirrhosis

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