amyotrophic lateral sclerosis

noun
amyo·​tro·​phic lateral sclerosis | \ ˌā-ˌmī-ə-ˈtrō-fik- How to pronounce amyotrophic lateral sclerosis (audio) , -ˈträ- How to pronounce amyotrophic lateral sclerosis (audio) \

Definition of amyotrophic lateral sclerosis

: a rare progressive degenerative fatal disease affecting the motor neurons, usually beginning in middle age, and characterized especially by increasing and spreading muscular weakness and atrophy abbreviation ALS

called also Lou Gehrig's disease

Examples of amyotrophic lateral sclerosis in a Sentence

Recent Examples on the Web Gehrig was diagnosed with amyotrophic lateral sclerosis, now called Lou Gehrig’s Disease, and was forced to retire a few weeks later. John Scheibe, Los Angeles Times, "This day in sports: Yankees great Lou Gehrig ends his ironman streak," 2 May 2020 Drugs are in development for rare diseases such as amyotrophic lateral sclerosis (ALS) for which there was previously no hope of treatment. Lydia Denworth, Scientific American, "A Breakthrough in Genetic Medicine for Rare Diseases," 3 Mar. 2020 But now, two years later, Darlene, 61, is alone, her husband struck down by amyotrophic lateral sclerosis within months of the shocking diagnosis in August 2018. Sean P. Murphy, BostonGlobe.com, "A paperwork glitch cuts a widow’s pension payment nearly in half," 12 Jan. 2020 Turner lost his life to amyotrophic lateral sclerosis in 2016, a disease that was attributed to chronic traumatic encephalopathy. Mark Inabinett | Minabinett@al.com, al, "How many Alabama players have been picked in the NFL Draft?," 9 Apr. 2020 Lou Gehrig’s disease, also known as amyotrophic lateral sclerosis or motor neuron disease, is a progressive neurodegenerative disease that leads to paralysis due to the death of motor neurons in the spinal cord and brain. chicagotribune.com, "Pete Frates, one of the inspirations for the Ice Bucket Challenge, dies at 34," 9 Dec. 2019 In humans, some disorders have been linked to malfunctions of RNA editing, such as the sporadic form of amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's Disease. Eric Niiler, Wired, "Squids' Gene-Editing Superpowers May Unlock Human Cures," 24 Mar. 2020 It also put in reach a tantalizing set of neurological targets such as Huntington’s disease and amyotrophic lateral sclerosis (ALS). Lydia Denworth, Scientific American, "A Breakthrough in Genetic Medicine for Rare Diseases," 3 Mar. 2020 Does a patient survive cancer just to develop another terrible disease, like amyotrophic lateral sclerosis (ALS), in fifteen years? Jacqueline Detwiler, Popular Mechanics, "Health," 1 Feb. 2020

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'amyotrophic lateral sclerosis.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of amyotrophic lateral sclerosis

1875, in the meaning defined above

History and Etymology for amyotrophic lateral sclerosis

a- entry 2 + my- + -trophic

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Time Traveler for amyotrophic lateral sclerosis

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The first known use of amyotrophic lateral sclerosis was in 1875

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Last Updated

13 May 2020

Cite this Entry

“Amyotrophic lateral sclerosis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/amyotrophic%20lateral%20sclerosis. Accessed 24 May. 2020.

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More Definitions for amyotrophic lateral sclerosis

amyotrophic lateral sclerosis

noun

Medical Definition of amyotrophic lateral sclerosis

: a rare fatal progressive degenerative disease that affects pyramidal motor neurons, usually begins in middle age, and is characterized especially by increasing and spreading muscular weakness abbreviation ALS

called also Lou Gehrig's disease

More from Merriam-Webster on amyotrophic lateral sclerosis

Britannica.com: Encyclopedia article about amyotrophic lateral sclerosis

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