amaurosis

noun

am·au·ro·sis | \ ˌa-mȯ-ˈrō-səs

plural amauroses\ -ˌsēz

Definition of amaurosis

: partial or complete loss of sight occurring especially without an externally perceptible change in the eye

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Examples of amaurosis in a Sentence

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Created by Spark Therapeutics, the treatment is for people with vision loss from mutations in the gene RPE65 leading to Leber congenital amaurosis (LCA) and RP and some other conditions. — Caren Chesler, Popular Mechanics, "A Vision Quest," 6 Mar. 2019 Caspian was born with a rare, inherited eye disorder called Leber congenital amaurosis, which results in the progressive deterioration of the retina, the tissue at the back of the eye that detects light and color. — Sumathi Reddy, WSJ, "High Hopes for a Gene Therapy Come With Fears Over Cost," 24 Sep. 2018 Luxturna treats patients with a faulty RPE65 gene, which includes patients with Leber congenital amaurosis and retinitis pigmentosa. — Sumathi Reddy, WSJ, "High Hopes for a Gene Therapy Come With Fears Over Cost," 24 Sep. 2018 But Leber congenital amaurosis is a progressive disease and with no treatment, Creed could one day be completely blind. — Naseem S. Miller, OrlandoSentinel.com, "Mount Dora boy among first to receive approved gene therapy drug for eye disease," 23 Mar. 2018 Luxturna was designed to address the RPE65 genetic mutation — in the best cases, permanently — for patients who have RPE65-associated retinitis pigmentosa or leber congenital amaurosis. — Julia Belluz, Vox, "Doctors just used a brand new gene therapy to try to save a child’s vision," 22 Mar. 2018 The boy, Creed Pettit, has a rare retinal disease called Leber congenital amaurosis. — Kate Sheridan, Newsweek, "Blind Boy Might Be Able to See Again After New Breakthrough Gene Therapy Surgery," 21 Mar. 2018 Spark’s therapy is for Leber congenital amaurosis, a defect in a gene called RPE65. — Linda Loyd, Philly.com, "FDA approves Spark's gene therapy for rare blindness pioneered at CHOP," 19 Dec. 2017 Eye doctors, parents and patients were unanimous in their support of approving the treatment, which would be aimed at the one in a million children with a specific genetic defect that causes Leber congenital amaurosis, or LCA for short. — Maggie Fox, NBC News, "FDA Panel Advises Approval of Gene Therapy for Blinding Disease," 12 Oct. 2017

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