reaction

noun

re·​ac·​tion rē-ˈak-shən 

1

a

: the act or process or an instance of reacting

b

: resistance or opposition to a force, influence, or movement

especially : tendency toward a former and usually outmoded political or social order or policy

2

: a response to some treatment, situation, or stimulus

her stunned reaction to the news

also : such a response expressed verbally

critical reaction to the play

3

: bodily response to or activity aroused by a stimulus:

a

: an action induced by vital resistance to another action

especially : the response of tissues to a foreign substance (such as an antigen or infectious agent)

b

: depression or exhaustion due to excessive exertion or stimulation

c

: heightened activity and overaction succeeding depression or shock

d

: a mental or emotional disorder forming an individual's response to their life situation

4

: the force that a body subjected to the action of a force from another body exerts in the opposite direction

5

a(1)

: chemical transformation or change : the interaction of chemical entities

(2)

: the state resulting from such a reaction

b

: a process involving change in atomic nuclei

Synonyms of reaction

• response
• answer

Examples of reaction in a Sentence

Their reaction to the news was positive.

When I told him what happened, his immediate reaction was one of shock.

The announcement produced an angry reaction from most of the people at the meeting.

My first reaction when I met him was not to trust him.

There hasn't yet been much reaction to the announcement.

There has been strong reaction against the government's policies.

A good driver has quick reactions.

The speed of his reactions saved his life.

Recent Examples on the Web

He was also sent off for a headbutt against an opponent who provoked him in his last ever match, which happened to be the 2006 World Cup final; his human reaction laid bare on the highest stage of all. — Amy Lawrence, New York Times, 21 July 2026

The bodycam video also sparked reaction online, with several conservative accounts criticizing Hostin for invoking her legal background during the encounter. — Stepheny Price, FOXNews.com, 21 July 2026

Very early in the morning, however, the moon will make a series of aspects — with Mars, Saturn and Mercury retrograde — that could potentially trigger everything from feelings of restlessness to emotional reactions due to mixed signals. — Valerie Mesa, PEOPLE, 20 July 2026

The announcement drew a mixed reaction from sellers in the forum where Amazon posted the update. — Arthur Zaczkiewicz, Footwear News, 20 July 2026

Word History

First Known Use

1585, in the meaning defined at sense 1a

Phrases Containing reaction

• alarm reaction
• chain reaction
• chemical reaction
• counter-reaction
• cross-reaction
• dark reaction
• Feulgen reaction
• Hill reaction
• in reaction to
• light reaction
• Maillard reaction
• mixed reaction
• nuclear reaction
• polymerase chain reaction
• reaction GIF
• Wassermann reaction

Rhymes for reaction

• action
• faction
• fraction
• traction
• abstraction
• attraction
• compaction
• contraction
• detraction
• diffraction
• distraction
• exaction

Kids Definition

reaction

noun

re·​ac·​tion rē-ˈak-shən 

1

a

: the act or process or an instance of reacting

our reaction to the news

b

: an action or attitude opposing current political or social forces or ideas

2

: a bodily response to a stimulus

especially : the response of the body to a foreign substance (as a drug)

3

: the force that opposes the action of a force applied to one body by another body

4

a

: chemical transformation or change : the action between atoms or molecules to form one or more new substances

b

: a process involving change in atomic nuclei

Medical Definition

reaction

noun

re·​ac·​tion rē-ˈak-shən 

1

: the act or process or an instance of reacting

2

: bodily response to or activity aroused by a stimulus:

a

: an action induced by vital resistance to another action

especially : the response of tissues to a foreign substance (as an antigen or infectious agent)

b

: depression or exhaustion due to excessive exertion or stimulation

c

: abnormally heightened activity succeeding depression or shock

d

: a mental or emotional disorder forming an individual's response to his or her life situation

3

: the force that a body subjected to the action of a force from another body exerts in the opposite direction

4

a(1)

: chemical transformation or change : the interaction of chemical entities

(2)

: the state resulting from such a reaction

b

: a process involving change in atomic nuclei