prebiotic

1 of 2

adjective

pre·​bi·​ot·​ic ˌprē-bī-ˈä-tik 

1

: of, relating to, or being chemical or environmental precursors of the origin of life

… it is possible that either the prebiotic molecules necessary for the evolution of life or the raw materials from which these molecules formed were brought to Earth by comet-like objects.

—Marcia Neugebauer

also : existing or occurring before the origin of life

… RNA is a chemically fragile molecule, unlikely to survive the harsh prebiotic conditions.

—Michael Egholm et al.

2

: of, relating to, or being a prebiotic

… next-generation probiotic microbes administered along with the appropriate prebiotic nutrients to nourish them.

—Michael Pollan

prebiotic

2 of 2

noun

: a substance and especially a carbohydrate (such as inulin) that is nearly or wholly indigestible and that when consumed (as in food) promotes the growth of beneficial bacteria in the digestive tract

Prebiotics are naturally found in certain fruits, vegetables, and herbs, including artichoke, asparagus, bananas, chicory, garlic, and onions.

—Andrew Weil

compare probiotic

Examples of prebiotic in a Sentence

Recent Examples on the Web

Adjective

Phosphite is more soluble in water than phosphate and has been proposed before as a prebiotic source of phosphorus. — Philip Ball, Scientific American, 20 Aug. 2026

The prebiotic fiber in avocados serves as fuel for beneficial gut bacteria or probiotics. — Randi Gollin, Martha Stewart, 15 Aug. 2026

Noun

Colostrum also contains prebiotics and immune-supporting compounds, which help feed beneficial gut bacteria, prevent harmful germs from attaching to the gut wall, and support a more balanced immune response. — Cheryl Fenton, Flow Space, 17 Aug. 2026

Probiotics are often paired with prebiotics, which feed those beneficial bacteria. — Lauren Jarvis-Gibson, Kansas City Star, 11 Aug. 2026

Word History

Etymology

Adjective

pre- + biotic

First Known Use

Adjective

1954, in the meaning defined at sense 1

Noun

1995, in the meaning defined above

Rhymes for prebiotic

• aprotic
• aquatic
• biotic
• chaotic
• cirrhotic
• demotic
• despotic
• dichotic
• erotic
• euphotic
• exotic
• fibrotic

Medical Definition

prebiotic

1 of 2 adjective

pre·​bi·​ot·​ic

-bī-ˈät-ik

1

: of, relating to, or being chemical or environmental precursors of the origin of life

prebiotic molecules

also : existing or occurring before the origin of life

prebiotic conditions

2

: of, relating to, or being a prebiotic

Prebiotic agents included the oligosaccharides inulin, galactose, fructose, lactulose, and combinations of these nutrients.

—Josef Neu et al., The New England Journal of Medicine

prebiotically

-i-k(ə-)lē

adverb

prebiotic

2 of 2 noun

: a substance and especially a carbohydrate (such as inulin) that is nearly or wholly indigestible and that when consumed (as in food) promotes the growth of beneficial bacteria in the digestive tract compare probiotic