open-label
adjective
open-la·bel
ˌō-pən-ˈlā-bəl 
: being or relating to a clinical trial in which the treatment given to each subject is not concealed from either the researchers or the subject
an open-label multicenter study
compare double-blind, single-blind
Examples of open-label in a Sentence
Recent Examples on the Web
The surprise finding involved what scientists call an open-label placebo.
—
Samantha Agate, Kansas City Star, 13 June 2026
Why a Learned Response May Explain the Relief Mills and his team suggest the open-label placebo effect may be rooted in years of conditioning.
—Samantha Agate, Miami Herald, 12 June 2026
The evidence base here consists primarily of preclinical rodent data, open-label case series, and in some instances a single research group’s publication that has not been independently replicated.
—Robert Glatter, Forbes.com, 4 June 2026
The scientific evidence behind the drug so far consists mostly of small observational studies and open-label trials.
—Kerry Breen, CBS News, 18 Apr. 2026
Two weeks later, everybody involved in the study got an open-label dose.
—ArsTechnica, 18 Feb. 2026
Psilocybin with psychological support for treatment-resistant depression: An open-label feasibility study.
—Josh Hammer, MSNBC Newsweek, 21 Apr. 2025
The company is conducting an open-label extension trial to assess the long-term safety and efficacy of brilaroxazine in patients with stable schizophrenia.
—Quartz Intelligence Newsroom, Quartz, 3 Apr. 2025
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Samantha Agate, Kansas City Star, 13 June 2026
Why a Learned Response May Explain the Relief Mills and his team suggest the open-label placebo effect may be rooted in years of conditioning.
—Samantha Agate, Miami Herald, 12 June 2026
The evidence base here consists primarily of preclinical rodent data, open-label case series, and in some instances a single research group’s publication that has not been independently replicated.
—Robert Glatter, Forbes.com, 4 June 2026
The scientific evidence behind the drug so far consists mostly of small observational studies and open-label trials.
—Kerry Breen, CBS News, 18 Apr. 2026
Two weeks later, everybody involved in the study got an open-label dose.
—ArsTechnica, 18 Feb. 2026
Psilocybin with psychological support for treatment-resistant depression: An open-label feasibility study.
—Josh Hammer, MSNBC Newsweek, 21 Apr. 2025
The company is conducting an open-label extension trial to assess the long-term safety and efficacy of brilaroxazine in patients with stable schizophrenia.
—Quartz Intelligence Newsroom, Quartz, 3 Apr. 2025
Cite this Entry
“Open-label.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/open-label. Accessed 25 Jun. 2026.
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