open-label

adjective

open-la·​bel ˌō-pən-ˈlā-bəl 

: being or relating to a clinical trial in which the treatment given to each subject is not concealed from either the researchers or the subject

an open-label multicenter study

compare double-blind, single-blind

Examples of open-label in a Sentence

Recent Examples on the Web

The surprise finding involved what scientists call an open-label placebo. — Samantha Agate, Kansas City Star, 13 June 2026

Why a Learned Response May Explain the Relief Mills and his team suggest the open-label placebo effect may be rooted in years of conditioning. — Samantha Agate, Miami Herald, 12 June 2026

The evidence base here consists primarily of preclinical rodent data, open-label case series, and in some instances a single research group’s publication that has not been independently replicated. — Robert Glatter, Forbes.com, 4 June 2026

The scientific evidence behind the drug so far consists mostly of small observational studies and open-label trials. — Kerry Breen, CBS News, 18 Apr. 2026

Word History

First Known Use

1979, in the meaning defined above

Rhymes for open-label

• allocable
• educable
• irrigable
• purchasable
• thermostable
• able
• chaebol
• fable
• label
• sable
• stabile
• stable

Medical Definition

open-label

adjective

: being or relating to a clinical trial in which the treatment given to each subject is not concealed from either the researchers or the subject

long-term open-label studies

compare double-blind, single-blind