open-label
adjective
open-la·bel
ˌō-pən-ˈlā-bəl 
: being or relating to a clinical trial in which the treatment given to each subject is not concealed from either the researchers or the subject
an open-label multicenter study
compare double-blind, single-blind
Examples of open-label in a Sentence
Recent Examples on the Web
Earlier this year, the company launched an open-label clinical trial at Sydney’s Mater Hospital and announced the successful dosing of its first patient.
—
Heather Farmbrough, Forbes.com, 1 Jan. 2026
Psilocybin with psychological support for treatment-resistant depression: An open-label feasibility study.
—Josh Hammer, MSNBC Newsweek, 21 Apr. 2025
The company is conducting an open-label extension trial to assess the long-term safety and efficacy of brilaroxazine in patients with stable schizophrenia.
—Quartz Intelligence Newsroom, Quartz, 3 Apr. 2025
So far, the growing body of study into open-label placebos has revealed positive effects in patients with back pain, nausea, IBS and migraine.
—New Atlas, 22 Feb. 2025
Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial.
—Matt Rozo, The Mercury News, 6 Jan. 2025
Two more died during a subsequent open-label safety study, in which everyone could opt for donanemab.
—science.org, 3 July 2024
Of these, 12 participants completed the study and enrolled in the open-label extension study.
—Sacramento Bee, 3 Apr. 2024
While the idea of the placebo response goes back as far as the ancient Greeks, the open-label placebo has a more recent history.
—Tom Vanderbilt, WIRED, 19 Dec. 2023
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Heather Farmbrough, Forbes.com, 1 Jan. 2026
Psilocybin with psychological support for treatment-resistant depression: An open-label feasibility study.
—Josh Hammer, MSNBC Newsweek, 21 Apr. 2025
The company is conducting an open-label extension trial to assess the long-term safety and efficacy of brilaroxazine in patients with stable schizophrenia.
—Quartz Intelligence Newsroom, Quartz, 3 Apr. 2025
So far, the growing body of study into open-label placebos has revealed positive effects in patients with back pain, nausea, IBS and migraine.
—New Atlas, 22 Feb. 2025
Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial.
—Matt Rozo, The Mercury News, 6 Jan. 2025
Two more died during a subsequent open-label safety study, in which everyone could opt for donanemab.
—science.org, 3 July 2024
Of these, 12 participants completed the study and enrolled in the open-label extension study.
—Sacramento Bee, 3 Apr. 2024
While the idea of the placebo response goes back as far as the ancient Greeks, the open-label placebo has a more recent history.
—Tom Vanderbilt, WIRED, 19 Dec. 2023
Cite this Entry
“Open-label.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/open-label. Accessed 11 Feb. 2026.
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