Definition of nodule
: a small mass of rounded or irregular shape: such as
a
: a small rounded lump of a mineral or mineral aggregate
b
: a swelling on a leguminous root that contains symbiotic bacteria
c
: a small abnormal knobby bodily protuberance (such as a tumorous growth or a calcification near an arthritic joint)
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Merriam-Webster unabridged
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Time Traveler for nodule
The first known use of nodule was in the 15th century
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