Definition of nicotinic
: relating to, resembling, producing, or mediating the effects produced by nicotine on nerve fibers at autonomic ganglia and at the neuromuscular junctions of voluntary muscle which increases activity in small doses and inhibits it in larger doses
nicotinic receptors
— compare muscarinic
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Merriam-Webster unabridged
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Time Traveler for nicotinic
The first known use of nicotinic was in 1941
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