: a poisonous alkaloid C10H14N2 that is the chief active principle of tobacco and is used as an insecticide

Examples of nicotine in a Sentence

Recent Examples on the Web
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There were broad reductions in alcohol, cannabis, cocaine, nicotine and opioid use. Jesse M. Pines, Forbes.com, 10 Aug. 2026 Jackler says he's seen many patients with complications from nicotine use. Joseph Kim, NPR, 5 Aug. 2026 Marketing nicotine pouch flavors like Rich Berry, Cappuccino, Citrus and Cinnamon raises particular concerns for health advocates because of their potential appeal to kids. Callie Teitelbaum, CBS News, 5 Aug. 2026 Meanwhile, 18-to-25-year-olds saw declines in the use of nicotine products, tobacco, cigarette, alcohol and binge drinking in the past month as well as the use of illicit drugs and prescription stimulants or opioids within the past year. Mary Kekatos, ABC News, 1 Aug. 2026 See All Example Sentences for nicotine

Word History

Etymology

French, from New Latin nicotiana

First Known Use

1817, in the meaning defined above

Time Traveler
The first known use of nicotine was in 1817

Cite this Entry

“Nicotine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/nicotine. Accessed 12 Aug. 2026.

Kids Definition

nicotine

noun
: a poisonous substance found in tobacco and used as an insecticide

Medical Definition

nicotine

noun
: a poisonous alkaloid C10H14N2 that is the chief active principle of tobacco and that is used as an insecticide and is sometimes used in smoking cessation aids

Note: Trademarks for nicotine include Nicoderm, Nicorette, and Nicotrol.

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