mus·​ca·​rin·​ic | \ ˌmə-skə-ˈri-nik How to pronounce muscarinic (audio) \

Definition of muscarinic

: of, relating to, resembling, producing, or mediating the parasympathetic effects (such as a slowed heart rate and increased activity of smooth muscle) produced by muscarine muscarinic receptors — compare nicotinic

Examples of muscarinic in a Sentence

Recent Examples on the Web The Karuna drug, called KarXT, works by targeting muscarinic acetylcholine receptors in the brain. Adam Feuerstein, STAT, 18 Nov. 2019 All nerve agent victims are given atropine, which blocks muscarinic acetylcholine receptors. Richard Stone, Science | AAAS, 19 Mar. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'muscarinic.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of muscarinic

1936, in the meaning defined above

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The first known use of muscarinic was in 1936

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Cite this Entry

“Muscarinic.” Dictionary, Merriam-Webster, Accessed 14 Aug. 2022.

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More Definitions for muscarinic


mus·​ca·​rin·​ic | \ -kə-ˌrin-ik How to pronounce muscarinic (audio) \

Medical Definition of muscarinic

: relating to, resembling, producing, or mediating the effects (as a slowed heart rate, increased secretion by exocrine glands, and increased activity of smooth muscle) that are produced on organs and tissues by acetylcholine liberated by postganglionic nerve fibers of the parasympathetic nervous system and that are mimicked by muscarine muscarinic receptors atropine is a muscarinic antagonist — compare nicotinic


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