mus·​ca·​rin·​ic | \ ˌmə-skə-ˈri-nik How to pronounce muscarinic (audio) \

Definition of muscarinic

: of, relating to, resembling, producing, or mediating the parasympathetic effects (such as a slowed heart rate and increased activity of smooth muscle) produced by muscarine muscarinic receptors — compare nicotinic

Examples of muscarinic in a Sentence

Recent Examples on the Web The Karuna drug, called KarXT, works by targeting muscarinic acetylcholine receptors in the brain. Adam Feuerstein, STAT, "A new approach to treating schizophrenia delivers positive results in mid-stage trial," 18 Nov. 2019 All nerve agent victims are given atropine, which blocks muscarinic acetylcholine receptors. Richard Stone, Science | AAAS, "U.K. attack shines spotlight on deadly nerve agent developed by Soviet scientists," 19 Mar. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'muscarinic.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of muscarinic

1936, in the meaning defined above

Keep scrolling for more

Learn More about muscarinic

Time Traveler for muscarinic

Time Traveler

The first known use of muscarinic was in 1936

See more words from the same year

Statistics for muscarinic

Cite this Entry

“Muscarinic.” Dictionary, Merriam-Webster, Accessed 14 May. 2021.

Style: MLA
MLACheck Mark Icon ChicagoCheck Mark Icon APACheck Mark Icon Merriam-WebsterCheck Mark Icon

Keep scrolling for more

More Definitions for muscarinic


mus·​ca·​rin·​ic | \ -kə-ˌrin-ik How to pronounce muscarinic (audio) \

Medical Definition of muscarinic

: relating to, resembling, producing, or mediating the effects (as a slowed heart rate, increased secretion by exocrine glands, and increased activity of smooth muscle) that are produced on organs and tissues by acetylcholine liberated by postganglionic nerve fibers of the parasympathetic nervous system and that are mimicked by muscarine muscarinic receptors atropine is a muscarinic antagonist — compare nicotinic

Comments on muscarinic

What made you want to look up muscarinic? Please tell us where you read or heard it (including the quote, if possible).


Test Your Vocabulary

Words Used by Nabokov Quiz

  • image1676440788
  • Choose the best definition or synonym for the word in bold: "There are some eructations that sound like cheers—at least, mine did." Lolita
Name That Thing

Test your visual vocabulary with our 10-question challenge!

 AlphaBear 2

Spell words. Make bears.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!