neuraminidase

noun
neur·​amin·​i·​dase | \ ˌnu̇r-ə-ˈmi-nə-ˌdās How to pronounce neuraminidase (audio) , ˌnyu̇r-, -ˌdāz \

Definition of neuraminidase

: a hydrolytic enzyme that occurs on the surface of the pneumococcus, influenza-causing viruses, and some paramyxoviruses as an antigen and that splits mucoproteins by breaking a glucoside link

Examples of neuraminidase in a Sentence

Recent Examples on the Web Viral code The Hs and Ns refer to hemagglutinin (Ha or H) and neuraminidase (Na or N), respectively, which are both viral molecules that hang on the outside of viral particles. Beth Mole, Ars Technica, "Unusual type of flu virus is dominating early start to this year’s flu season," 10 Dec. 2019 The flu virus normally infects cells in the lungs by binding through its haemagglutinin and neuraminidase proteins to sialic acid on the surface of lung cells. Neil Savage, Scientific American, "The push for better flu therapies," 18 Sep. 2019 Virologists classify these viruses into subtypes based on two proteins on their surface, haemagglutinin (H) and neuraminidase (N). Cassandra Willyard, Scientific American, "Flu on the Farm," 18 Sep. 2019 They are classified by numbers based on the subtype of haemagglutinin (H) protein and a second viral protein known as neuraminidase (N), with even greater strain variation observed among those subtypes. Michael Eisenstein, Scientific American, "Towards a universal flu vaccine," 18 Sep. 2019 These drugs inhibit neuraminidase, an enzyme that allows viruses to escape from one cell and spread to others. Neil Savage, Scientific American, "The push for better flu therapies," 18 Sep. 2019 Another neuraminidase inhibitor, peramivir, which is administered intravenously, has been approved for use in the United States, Japan and South Korea. Neil Savage, Scientific American, "The push for better flu therapies," 18 Sep. 2019 There are only two other classes of flu drugs, neuraminidase inhibitors (drugs like Tamiflu, Relenza, Rapivab) and the adamantane drugs (amantadine and rimantadine). Helen Branswell, STAT, "A flu drug — shown to reduce the duration of symptoms — could upend treatment in U.S.," 27 June 2018 All three are in a class called neuraminidase inhibitors. NBC News, "New, fast-acting flu drug gets priority FDA review," 26 June 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'neuraminidase.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of neuraminidase

1957, in the meaning defined above

History and Etymology for neuraminidase

neuraminic acid, an amino acid + -ide + -ase

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Time Traveler for neuraminidase

Time Traveler

The first known use of neuraminidase was in 1957

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Cite this Entry

“Neuraminidase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/neuraminidase. Accessed 25 Oct. 2020.

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More Definitions for neuraminidase

neuraminidase

noun
neur·​amin·​i·​dase | \ ˌn(y)u̇r-ə-ˈmin-ə-ˌdās, -ˌdāz How to pronounce neuraminidase (audio) \

Medical Definition of neuraminidase

: a hydrolytic enzyme that occurs on the surface of the pneumococcus, the orthomyxoviruses, and some paramyxoviruses and that cleaves terminal acetylated neuraminic acids from sugar residues (as in glycoproteins and mucoproteins)

More from Merriam-Webster on neuraminidase

Britannica.com: Encyclopedia article about neuraminidase

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