mono·​nu·​cle·​ar ˌmä-nə-ˈnü-klē-ər How to pronounce mononuclear (audio)
-kyə-lər How to pronounce mononuclear (audio)
: having only one nucleus
a mononuclear cell
mononuclear noun

Examples of mononuclear in a Sentence

Recent Examples on the Web To deliver the therapy, clinicians draw a group of cells called bone marrow mononuclear cells from patients’ hips. Andrew Joseph, STAT, 13 Apr. 2018

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'mononuclear.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


International Scientific Vocabulary

First Known Use

1886, in the meaning defined above

Time Traveler
The first known use of mononuclear was in 1886

Dictionary Entries Near mononuclear

Cite this Entry

“Mononuclear.” Dictionary, Merriam-Webster, Accessed 30 May. 2024.

Medical Definition


1 of 2 adjective
mono·​nu·​cle·​ar ˌmän-ō-ˈn(y)ü-klē-ər How to pronounce mononuclear (audio)
: having only one nucleus
a mononuclear cell


2 of 2 noun
: a mononuclear cell
especially : monocyte
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