microdose

1 of 2

noun

mi·​cro·​dose ˈmī-krō-ˌdōs How to pronounce microdose (audio)
plural microdoses
: an extremely small dose
The province has shifted to making a microdose of the measles vaccine available for infants under age one who are not yet old enough for their first full vaccination but still at risk of severe measles complications.Jackie Carmichael
especially : a smaller than typical amount taken of a psychoactive substance (such as THC or LSD)
These self-experimenters take a very small amount of … LSD to try to reduce anxiety, stress and depression. Some claim the practice gives them access to joy, creativity and connection they can't get otherwise. This isn't a full-blown acid trip—or even close. If you see visions, it's not a microdose. Carla K. Johnson
There's no set definition for a microdose. But it's generally considered to be 1/5 to 1/20 of a recreational dose. A psilocybin microdose is typically about 0.3 grams of dried mushroom. Deanna Altomara
sometimes used before another noun
microdose THC

microdose

2 of 2

verb

variants or less commonly micro-dose
microdosed also micro-dosed; microdosing also micro-dosing; microdoses also micro-doses
1
transitive + intransitive : to take or administer a very small amount of a drug and especially a psychoactive substance (such as THC or LSD) : to take or administer a microdose
Instead of throwing in the towel on the sleep aid, many people are now microdosing melatonin as an ideal way to use this supplement.Gayle Guyardo
A person who microdoses LSD typically takes about 10 micrograms, just a tenth or twentieth of the amount normally taken for a "trip," or psychedelic experience …Franziska Spiecker
At the start of the pandemic, I coped with my frayed nerves by exercising, meditating, even microdosing THC, all of which brought a modicum of relief.Annabelle Gurwitch
2
transitive : to add a microdose to (something)
Their Terra Milk Chocolate Bites are crafted with sustainably-sourced cacao and microdosed with THC, offering just enough to feel the effects without overwhelming your senses.Matt Rozo
microdoser noun
plural microdosers

Word History

Etymology

Noun

micro- + dose entry 1

Verb

derivative of microdose entry 1

First Known Use

Noun

1923, in the meaning defined above

Verb

1985, in the meaning defined at sense 1

Time Traveler
The first known use of microdose was in 1923

Browse Nearby Words

Cite this Entry

“Microdose.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/microdose. Accessed 10 Mar. 2026.

Medical Definition

microdose

noun
mi·​cro·​dose ˈmī-krō-ˌdōs How to pronounce microdose (audio)
: an extremely small dose
Last Updated: - Entry added
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