macrophage

noun
mac·​ro·​phage | \ ˈma-krə-ˌfāj How to pronounce macrophage (audio) \

Definition of macrophage

: a phagocytic tissue cell of the immune system that may be fixed or freely motile, is derived from a monocyte, functions in the destruction of foreign antigens (such as bacteria and viruses), and serves as an antigen-presenting cell — compare histiocyte

Other Words from macrophage

macrophagic \ ˌma-​krə-​ˈfa-​jik How to pronounce macrophage (audio) \ adjective

Examples of macrophage in a Sentence

Recent Examples on the Web One tactic: the squalene in a foamy macrophage’s belly finds oxygen radicals – molecules that can kill acne bacteria – and incorporates them into its oily stew, neutralizing the threat, letting acne flourish. Isabella Cueto, STAT, 23 July 2022 No such monocyte or macrophage infection was seen in the control group of healthy blood donors. William A. Haseltine, Forbes, 21 Apr. 2022 Otilimab is a monoclonal antibody against the granulocyte macrophage colony-stimulating factor, or GM-CSF, which stimulates the production of white blood cells. Matthew Herper, STAT, 27 Feb. 2021 Resolution Therapeutics, a macrophage cell therapy company, raised £26.8 million ($35 million). Lucinda Shen, Fortune, 14 Sep. 2020 Meanwhile, specialized white blood cells, called macrophages, gobble up free-floating virus as the body's first line of defense, according to Dr. Raphael Viscidi, an infectious disease specialist at Johns Hopkins Medicine. USA Today, 18 May 2020 That observation suggested the macrophages were immunosuppressive. Esther Landhuis, Scientific American, 27 Mar. 2020 Vitamin D boosts the function of macrophages and T-cells, members of the immune system that fight pathogens attempting to enter the body. Jill Langlois, National Geographic, 17 Apr. 2020 These bind with proteins on a virus’s surface, disabling it and marking it for destruction by cells called macrophages. The Economist, 1 Apr. 2020 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'macrophage.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of macrophage

1887, in the meaning defined above

History and Etymology for macrophage

borrowed from German Makrophagen (plural), from makro- macro- + -phagen, plural of -phage -phage

Note: Introduced, along with Mikrophagen "microphages," by Élie metchnikoff in "Ueber den Kampf der Zellen gegen Erysipelkokken," Archiv für pathologische Anatomie und Physiologie, Band 107 (1887), p. 222.

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The first known use of macrophage was in 1887

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Dictionary Entries Near macrophage

macroorganism

macrophage

macrophagous

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Last Updated

25 Jul 2022

Cite this Entry

“Macrophage.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/macrophage. Accessed 19 Aug. 2022.

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More Definitions for macrophage

macrophage

noun
mac·​ro·​phage | \ ˈmak-rə-ˌfāj How to pronounce macrophage (audio) , -ˌfäzh How to pronounce macrophage (audio) \

Medical Definition of macrophage

: a phagocytic tissue cell of the immune system that may be fixed or freely motile, is derived from a monocyte, functions in the destruction of foreign antigens (as bacteria and viruses), and serves as an antigen-presenting cell — see histiocyte, mononuclear phagocyte system

Other Words from macrophage

macrophagic \ ˌmak-​rə-​ˈfaj-​ik How to pronounce macrophage (audio) \ adjective

More from Merriam-Webster on macrophage

Britannica.com: Encyclopedia article about macrophage

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