macrophage

noun
mac·​ro·​phage | \ ˈma-krə-ˌfāj How to pronounce macrophage (audio) \

Definition of macrophage

: a phagocytic tissue cell of the immune system that may be fixed or freely motile, is derived from a monocyte, functions in the destruction of foreign antigens (such as bacteria and viruses), and serves as an antigen-presenting cell — compare histiocyte

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Other Words from macrophage

macrophagic \ ˌma-​krə-​ˈfa-​jik How to pronounce macrophagic (audio) \ adjective

Examples of macrophage in a Sentence

Recent Examples on the Web

For instance, one pair of proteins involved in the clock, REV-ERBα and REV-ERBβ, tightly control the expression of genes key to the function of macrophages, the body’s attack cells. Quanta Magazine, "The Body’s Clock Offers a Rhythmic Target to Viruses," 30 May 2019 The wound current calls out to the surrounding tissue, attracting helpers like healing agents, macrophages to mop up the mess, and collagen-weaving repair cells called fibroblasts. Sally Adee, Quartz, "Our bodies are full of electricity that could help us fight cancer," 30 May 2019 Or macrophages, the cleanup crew of the bloodstream? William Poor, The Verge, "How deaf researchers are reinventing science communication," 11 Dec. 2018 For the cultured cells, exposure to e-cigarette vapor induced many of the same changes in lung macrophages that have been seen in cigarette smokers and patients with COPD, the researchers note. Fox News, "E-cigarette vapor tied to changes in lung cells," 15 Aug. 2018 To determine what effect vaporizing might have, Thickett and his colleagues extracted macrophages from lung tissue samples from eight non-smokers who had never had asthma or COPD. Fox News, "E-cigarette vapor tied to changes in lung cells," 15 Aug. 2018 Cancer cells avoid destruction by macrophages in two ways. Martin Finucane, BostonGlobe.com, "Brigham and Women’s researchers take another step toward using immune system to fight cancer," 2 July 2018 Her subject was macrophages, big, hungry cells on the front lines of the defense. Judith Shulevitz, New York Times, "Is Our Obsession With Wellness Doing Us In?," 11 June 2018 The initial immune response involves cells of the body’s innate immune system, such as macrophages and neutrophils. Laura Haynes, Washington Post, "How the flu hijacks your body to make you feel so wretched," 17 Feb. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'macrophage.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of macrophage

1887, in the meaning defined above

History and Etymology for macrophage

borrowed from German Makrophagen (plural), from makro- macro- + -phagen, plural of -phage -phage

Note: Introduced, along with Mikrophagen "microphages," by Élie metchnikoff in "Ueber den Kampf der Zellen gegen Erysipelkokken," Archiv für pathologische Anatomie und Physiologie, Band 107 (1887), p. 222.

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Statistics for macrophage

Last Updated

1 Jul 2019

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Time Traveler for macrophage

The first known use of macrophage was in 1887

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More Definitions for macrophage

macrophage

noun
mac·​ro·​phage | \ ˈmak-rə-ˌfāj How to pronounce macrophage (audio) , -ˌfäzh How to pronounce macrophage (audio) \

Medical Definition of macrophage

: a phagocytic tissue cell of the immune system that may be fixed or freely motile, is derived from a monocyte, functions in the destruction of foreign antigens (as bacteria and viruses), and serves as an antigen-presenting cell — see histiocyte, mononuclear phagocyte system

Other Words from macrophage

macrophagic \ ˌmak-​rə-​ˈfaj-​ik How to pronounce macrophagic (audio) \ adjective

More from Merriam-Webster on macrophage

Britannica.com: Encyclopedia article about macrophage

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