kinase

noun
ki·​nase | \ ˈkī-ˌnās How to pronounce kinase (audio) , -ˌnāz \

Definition of kinase

: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (such as ATP) to a substrate — compare protein kinase

Examples of kinase in a Sentence

Recent Examples on the Web One reason is fewer people are smoking, and improved treatments like epidermal growth-factor receptor tyrosine-kinase inhibitor are able to target non-small cell lung cancer mutations. The Editorial Board, WSJ, "The Good News on Cancer," 14 Jan. 2021 In blood cancers and some solid tumors, two of the current therapeutic targets that have garnered much interest are the proteins BCL-2 and Bruton tyrosine kinase (BTK). Scientific American, "An Ongoing Revolution in Blood Cancer," 1 Dec. 2020 The first breakout kinase inhibitor was approved in 2001 for a form of blood cancer, as was the first B-cell lymphoma (BCL) 2 inhibitor in 2016 and chimeric antigen receptor T (CAR-T) cell therapy in 2017. Scientific American, "An Ongoing Revolution in Blood Cancer," 1 Dec. 2020 Other cancer therapies, such as a class of drugs known as Bruton's tyrosine kinase inhibitors, may be protective and are being tested in coronavirus patients without cancer. Emily Woodruff, NOLA.com, "Having cancer and coronavirus is a dangerous combination, studies show," 6 Aug. 2020 One street that seemed particularly active was ruled by a kinase called Casein Kinase II, which happened to be one of the 332 proteins flagged in the team’s earlier protein map. Jason Fagone, SFChronicle.com, "‘There’s a cocktail out there that can cure this’: Inside a UCSF-led quest to exploit the coronavirus' weak spots," 26 June 2020 Among them was a compound called silmitasertib, which inhibits a kinase called CK2, and is being tested as a cancer drug. Gregory Barber, Wired, "Old Drugs Could Reveal a New Way to Attack the Coronavirus," 27 June 2020 The virus most powerfully hijacks a kinase called CK2, which plays a key role in the basic frame of the cell as well as its growth, proliferation and death. Mark Johnson, Milwaukee Journal Sentinel, "Study reveals images of the coronavirus forming tentacles in cells -- but monstrous discovery helps identify new treatment," 27 June 2020 The tests were performed by virologists at Mount Sinai and the Institut Pasteur, who infected host cells with the virus and added the kinase inhibitors. Jason Fagone, SFChronicle.com, "‘There’s a cocktail out there that can cure this’: Inside a UCSF-led quest to exploit the coronavirus' weak spots," 26 June 2020

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'kinase.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of kinase

1947, in the meaning defined above

History and Etymology for kinase

International Scientific Vocabulary, from kinetic

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Statistics for kinase

Cite this Entry

“Kinase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/kinase. Accessed 23 Apr. 2021.

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More Definitions for kinase

kinase

noun
ki·​nase | \ ˈkī-ˌnās, -ˌnāz How to pronounce kinase (audio) \

Medical Definition of kinase

: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (as ATP or ADP) to a substrate

called also phosphokinase

More from Merriam-Webster on kinase

Nglish: Translation of kinase for Spanish Speakers

Britannica.com: Encyclopedia article about kinase

Comments on kinase

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