Definition of kinase
: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (such as ATP) to a substrate — compare protein kinase
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Recent Examples of kinase from the Web
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Hunter made his reputation with the 1979 discovery of how enzymes called tyrosine kinases can cause cancer.
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Most recently, autoimmune drugs known as Janus kinase inhibitors -- JAK inhibitors -- have been found to produce a full head of hair in patients with moderate to severe alopecia areata, a type of baldness that affects both men and women.
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In February, for example, Hyman and co-authors reported in The New England Journal of Medicine that a drug aimed at genes known as tropomyosin receptor kinase (TRK) fusions works for many tumor types.
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Spectrum of discovery The Nature study can be viewed as an extension of Hunter’s groundbreaking work in tyrosine kinases.
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The class of cancer drugs that block phosphorylation activity are called tyrosine kinase inhibitors.
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The team at Stamford has previously determined the role of homeodomain-interacting protein kinase 4 (HIPK4) in the later stages of spermatogenesis, and it is thought that a drug targeting this kinase could be used as a contraceptive.
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Celgene is interested in Impact Biomedicines’ fedratinib, a kinase inhibitor that has shown promise as a potential treatment for a type of blood cancer called myelofibrosis, according to a statement put out jointly by both companies.
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Celgene is interested in Impact Biomedicines’ fedratinib, a kinase inhibitor that has shown promise as a potential treatment for a type of blood cancer called myelofibrosis, according to a statement put out jointly by both companies.
These example sentences are selected automatically from various online news sources to reflect current usage of the word 'kinase.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.
Origin and Etymology of kinase
International Scientific Vocabulary, from kinetic
Medical Dictionary
medical Definition of kinase
: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (as ATP or ADP) to a substrate — called also
phosphokinase
Learn More about kinase
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See words that rhyme with kinase Nglish: Translation of kinase for Spanish speakers Britannica.com: Encyclopedia article about kinase
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