ki·​nase ˈkī-ˌnās How to pronounce kinase (audio)
: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (such as ATP) to a substrate compare protein kinase

Examples of kinase in a Sentence

Recent Examples on the Web Physicians had indeed moved their patients over to one of the newer tyrosine kinase inhibitors like Tasigna. WIRED, 4 Sep. 2023 But the diagnostic test, which checks to see if a patient’s tumor carries a mutation in a gene coding for anaplastic lymphoma kinase, called ALK , is just $250. David Ewing Duncan, Discover Magazine, 30 Oct. 2012 This change results in person's bone marrow making a specific protein called tyrosine kinase, which causes too many stem cells to become white blood cells—and, as with other types of leukemia, those extra abnormal blood cells build up, leaving less room for healthy blood cells. Barbara Brody,, 30 Sep. 2021 You may then be given tyrosine kinase inhibitors (TKIs), targeted therapy drugs that send signals to the cells to stop that growth. Gagandeep Brar, Verywell Health, 19 Mar. 2023 Tyrosine kinase inhibitors also play an important role in the treatment of medullary cancer of the thyroid. Christine Coppa, Health, 15 Mar. 2023 Further work showed that the ovaries of the gamergates strongly expressed a protein, Imp-L2, that ignored the MAP kinase pathway but interfered with the second pathway in the fat body. Viviane Callier, Quanta Magazine, 10 Jan. 2023 Other synthetic DMARDs work against the Janus kinase enzyme. Dr. Keith Roach, oregonlive, 3 Feb. 2023 Pyrukynd is a pill for a hereditary blood disorder called pyruvate kinase deficiency. Globe Staff,, 12 July 2022 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'kinase.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


International Scientific Vocabulary, from kinetic

First Known Use

1947, in the meaning defined above

Time Traveler
The first known use of kinase was in 1947

Dictionary Entries Near kinase

Cite this Entry

“Kinase.” Dictionary, Merriam-Webster, Accessed 4 Dec. 2023.

Medical Definition


: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (as ATP or ADP) to a substrate

called also phosphokinase

More from Merriam-Webster on kinase

Last Updated: - Updated example sentences
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