ki·​nase | \ ˈkī-ˌnās How to pronounce kinase (audio) , -ˌnāz \

Definition of kinase

: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (such as ATP) to a substrate — compare protein kinase

Examples of kinase in a Sentence

Recent Examples on the Web Given as a pill, mitapivat is designed to activate an enzyme called pyruvate kinase-R that red blood cells use to convert sugars into energy. Adam Feuerstein, STAT, 18 Feb. 2022 The authors of the study identified TBK1 as another target of the M protein, a kinase critical to the phosphorylation of interferon responsive factor 3 (see Figure 2). William A. Haseltine, Forbes, 22 Sep. 2021 Cellular damage post-marathon is best measured by the presence and production of creatinine kinase (CK)—a marker that indicates damage to skeletal and myocardial tissue — and increased myoglobin levels in the blood stream. Jeff Gaudette, Outside Online, 22 Nov. 2019 In more severe cases, some patients may use Janus kinase inhibitors. NBC News, 7 Jan. 2022 Interleukin-6 inhibitors, and Janus kinase inhibitors. Sharon Guynup, Science, 29 Dec. 2021 That signal involves the production of a type of cytokine called a Janus kinase, or JAK. Marla Broadfoot, Scientific American, 1 Sep. 2021 As a student, Sabatini discovered the mTOR kinase signaling pathway, a central regulator of growth and aging that doesn’t function properly in common diseases including cancer. Meredith Wadman, Science | AAAS, 21 Aug. 2021 The startup is developing drugs that rely on enzyme blockers known as kinase inhibitors to keep cancer cells from growing., 29 July 2021 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'kinase.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of kinase

1947, in the meaning defined above

History and Etymology for kinase

International Scientific Vocabulary, from kinetic

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Cite this Entry

“Kinase.” Dictionary, Merriam-Webster, Accessed 28 May. 2022.

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More Definitions for kinase


ki·​nase | \ ˈkī-ˌnās, -ˌnāz How to pronounce kinase (audio) \

Medical Definition of kinase

: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (as ATP or ADP) to a substrate

called also phosphokinase

More from Merriam-Webster on kinase

Nglish: Translation of kinase for Spanish Speakers Encyclopedia article about kinase


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