kinase

noun

ki·​nase ˈkī-ˌnās 

-ˌnāz

: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (such as ATP) to a substrate compare protein kinase

Examples of kinase in a Sentence

Recent Examples on the Web

Physicians had indeed moved their patients over to one of the newer tyrosine kinase inhibitors like Tasigna. —WIRED, 4 Sep. 2023

But the diagnostic test, which checks to see if a patient’s tumor carries a mutation in a gene coding for anaplastic lymphoma kinase, called ALK , is just $250. —David Ewing Duncan, Discover Magazine, 30 Oct. 2012

This change results in person's bone marrow making a specific protein called tyrosine kinase, which causes too many stem cells to become white blood cells—and, as with other types of leukemia, those extra abnormal blood cells build up, leaving less room for healthy blood cells. —Barbara Brody, Health.com, 30 Sep. 2021

You may then be given tyrosine kinase inhibitors (TKIs), targeted therapy drugs that send signals to the cells to stop that growth. —Gagandeep Brar, Verywell Health, 19 Mar. 2023

Tyrosine kinase inhibitors also play an important role in the treatment of medullary cancer of the thyroid. —Christine Coppa, Health, 15 Mar. 2023

Further work showed that the ovaries of the gamergates strongly expressed a protein, Imp-L2, that ignored the MAP kinase pathway but interfered with the second pathway in the fat body. —Viviane Callier, Quanta Magazine, 10 Jan. 2023

Other synthetic DMARDs work against the Janus kinase enzyme. —Dr. Keith Roach, oregonlive, 3 Feb. 2023

Pyrukynd is a pill for a hereditary blood disorder called pyruvate kinase deficiency. —Globe Staff, BostonGlobe.com, 12 July 2022

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Word History

Etymology

International Scientific Vocabulary, from kinetic

First Known Use

1947, in the meaning defined above

Phrases Containing kinase

• creatine kinase
• protein kinase
• protein kinase C

• creatine kinase
• protein kinase
• protein kinase C

Medical Definition

kinase

noun

ki·​nase ˈkī-ˌnās, -ˌnāz 

: any of various enzymes that catalyze the transfer of phosphate groups from a high-energy phosphate-containing molecule (as ATP or ADP) to a substrate

called also phosphokinase